Inhibitors of PARP to Kill Cancer Cells
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 20 April 2025 | Viewed by 67
Special Issue Editor
Interests: sensors; organic devices; layer-by-layer films; solid state physics; optical devices; drug delivery systems; liposomes; Langmuir films; adsorption; effect of radiation on biological matter
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The therapeutic efficiency of cancer treatment can be maximized using molecules that can modulate radiation effects as DNA repair inhibitors. These molecules have specific cellular targets, such as Poly (ADP-ribose) polymerase-1 (PARP1), which are involved in DNA repair and can represent a new era for cancer therapy. This Special Issue of IJMS focuses on the latest developments in the synthesis of new DNA repair inhibitors and in the encapsulation of DNA repair inhibitor molecules on organic or inorganic nanoparticles, with biocompatibility, biodegradability, and low toxicity, to maximize the delivery of the DNA repair inhibitor molecules to cancer cells. This Special Issue, “Inhibitors of PARP to Kill Cancer Cells”, invites and encourages you to prepare review articles and full-length papers that explore the synthesis, the encapsulation, and the effect on cells in the presence of radiation of DNA repair inhibitor molecules. Moreover, papers providing new insights into the mechanisms associated with the role of the DNA repair inhibitor molecules on cancer cells are also encouraged.
Prof. Dr. Maria Raposo
Guest Editor
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Keywords
- DNA repair inhibitor molecules
- drug delivery systems
- nanoparticles
- phototherapy
- cancer
- DNA damage
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