Molecular Research of Endocytic and Autophagic Pathways in Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 February 2025 | Viewed by 2472
Special Issue Editors
2. Department of Neurosciences, Santa Maria Health School, 4049-024 Porto, Portugal
Interests: oncobiology; adrenocortical tumors; anticancer drugs; cancer drug resistance; cancer biomarkers; extracellular vesicles; intracellular trafficking pathways; endocytic pathway; endosomal-lysosomal system; autophagy; programmed cell death
2. Instituto de Ciências Biomédicas Abel Salazar, University of Porto, 4099-002 Porto, Portugal
Interests: adrenocortical tumors; obesity; bariatric surgery; signaling pathways
Special Issue Information
Dear Colleagues,
Different membrane trafficking pathways such as recycling, lysosomal or autophagic pathways are essential for cellular homeostasis. Therefore, alterations in the regulation of those intracellular trafficking routes have been associated with different pathologies including cancer, neurological disorders and metabolic diseases. Endocytic pathways play a pivotal role, since the endosome is a dynamic organelle, which is involved in the sorting of cargo for recycling, for degradation or even for the biogenesis of extracellular vesicles.
This Special Issue of International Journal of Molecular Sciences aims to bring together state-of-the-art original research and reviews on the molecular research of autophagic and endocytic pathways in diseases. Topics may include the study of the: i) paradoxical role of autophagy in diseases, ii) interdependency of intracellular trafficking routes, and iii) autophagic or endocytic players as potential biomarkers of disease. Articles on the development of new methodologies to assess the status of these intracellular trafficking pathways will also be considered.
Dr. Diana Sousa
Dr. Sofia S. Pereira
Guest Editors
Manuscript Submission Information
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Keywords
- autophagy
- endocytic pathway
- endosome
- multivesicular body
- autophagosome endosomal–lysosomal system
- extracellular vesicles
- intracellular trafficking pathways
- membrane fusion
- metabolism
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