Advances in Developmental Neurotoxicology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 1717
Special Issue Editor
Interests: molecular toxicology; developmental neurotoxicology; new psychoactive substances; cannabinoids; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Humans are daily exposed to toxic substances that may affect the nervous system. The developing brain is particularly vulnerable, compared to the adult brain, to toxicants exposure, due to the complex network of events occurring during brain development (e.g., neuronal/glia differentiation, migration, maturation, synaptogenesis, blood-brain barrier immaturity). Moreover, neurodevelopmental impairment has been increasingly correlated with neurodevelopmental disorders (e.g., autism, attention deficit hyperactivity disorder), making the mechanistic understanding of how toxicants may affect the developing brain highly relevant. Notably, developmental neurotoxicity assessment remains quite challenging, as the developmental outcomes depend on the substance, type of exposure, and the brain’s developmental stage at the time of exposure. This Special Issue welcomes reviews and original research contributions on the most recent advances in developmental neurotoxicology, including, but not limited, to the following topics:
- Molecular mechanisms underlying the adverse effects of exposure to toxicants (g., pesticides, biocides, industrial chemicals, heavy metals, pharmaceuticals, substances of abuse, or nanomaterials) during neurodevelopment;
- Cognitive and behavioral outcomes following exposure to toxicants during neurodevelopment;
- Identification of new biomarkers of neurodevelopmental neurotoxicity that may be used as diagnostic tools or therapeutic targets for neurodevelopmental disorders;
- New and improved models (g., in silico, in vitro, in vivo) for testing developmental neurotoxicity.
This Special Issue is supervised by Dr. João Pedro Silva and assisted by our Topical Advisory Panel Member Dr. Ana Filipa Sobral, [email protected] (University Institute of Health Sciences).
Dr. João Pedro Silva
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- developmental neurotoxicology
- neurodevelopmental models
- neurotoxicants
- neurodevelopmental disorders
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