Molecular Mechanisms in Tumorigenesis of NMSC
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 December 2024 | Viewed by 4159
Special Issue Editors
Interests: skin cancer; plastic surgery; breast surgery; flaps; lipectomy; tumorigenesis
Special Issue Information
Dear Colleagues,
Non-melanoma skin cancer (NMSC) presents the most frequent malignancy in humans, demonstrating a consistent and progressively increasing annual incidence rate. Basal cell carcinoma and squamous cell carcinoma account for the vast majority of NMSC. Although the mortality rates associated with these tumors are relatively low, they impose a substantial economic burden on healthcare systems due to their high prevalence. Moreover, they are linked to considerable morbidity, particularly in patients with facial tumors that cause extensive local damage. In line with the recent progress in the molecular basis of malignant tumors, NMSC has also received considerable attention during the last decade.
In this Special Issue of the International Journal of Molecular Sciences on ‘Molecular Mechanisms in Tumorigenesis of NMSC’ original studies and well-conducted review articles will be published, aiming to provide a comprehensive overview of the current knowledge on the molecular landscape of NMSC, including underlying (epi)genomic alterations and interactions with tumor microenvironment, opportunities and challenges of novel targeted therapeutic approaches, and the advantages of molecular profiling, biomarkers, and molecular monitoring, which will translate to improved clinical management of these patients. Looking forward to the latest research in molecular, non-purely clinical studies.
Dr. Konstantinos Seretis
Dr. Panagiotis Kouklis
Guest Editors
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Keywords
- skin cancer
- NMSC
- tumorigenesis
- genetics
- biomarkers
- biology
- microenvironment
- exosomes
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