ijms-logo

Journal Browser

Journal Browser

Advances in Nutritional Approach to the Neurodegenerative Diseases

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 20 February 2025 | Viewed by 1700

Special Issue Editors


E-Mail Website
Guest Editor
Department of Medicine and Aging Science, University “G. D’Annunzio”, Via dei Vestini, 66100 Chieti, Italy
Interests: inflammation; immunity; neurodegenerative diseases; neuroinflammation; anti-inflammatory effects of natural products; peripheral biomarkers research
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Medical, Oral and Biotechnological Sciences, Unit of Immunodiagnostic and Molecular Pathology, University “G.d’Annunzio”, Via Dei Vestini 31, 66100 Chieti, Italy
Interests: neuroimmunology; inflammation; cytokines; non-neuronal cholinergic system; peripheral biomarkers of neurodegeneration; inflammation/autoimmunity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Neurodegenerative diseases are among the major health conditions that affect neurons in the human brain and result in the progressive degeneration or death of nervous system cells. Examples of neurodegenerative diseases are Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis, Huntington’s disease, etc. representing incurable and debilitating conditions.

To date, among the therapeutic strategies to reduce the progression of these diseases, nutritional strategies, mainly aimed at alleviating the symptoms of patients, such as inflammation, metabolic alterations, dysbiosis of commensal microbiota, and loss of neuronal structures, are highly relevant and have already proven to be beneficial for some patients.

Furthermore, a close relationship has emerged between metabolic diseases, induced by overnutrition, and neurodegenerative diseases such as Alzheimer's and Parkinson's; personalized nutrition strategies have been suggested as preventative tools.

This research topic aims to collect original research studies, reviews, and case reports which focus on new nutritional strategies to improve patient well-being. Furthermore, we also aim to collect studies that focus on the biological mechanisms of the activity of supplements, nutraceuticals, and other alternative medicine approaches that have the potential to significantly influence the health and quality of the lives of patients affected by neurodegenerative diseases.

We invite you to submit your research articles and reviews in order to expand knowledge and identify research gaps with innovative studies on developing new nutritional approaches.

Dr. Erica Costantini
Dr. Marcella Reale
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neurodegenerative disease
  • inflammation and oxidation
  • the interaction of brain and nutrition
  • nutritional preventive and therapeutic approaches
  • gut microbiota–brain axis
  • improving the quality of life in patients with neurodegenerative diseases

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

25 pages, 1598 KiB  
Review
Obesity Control and Supplementary Nutraceuticals as Cofactors of Brain Plasticity in Multiple Sclerosis Populations
by Lorena Ciumărnean, Oliviu-Florențiu Sârb, Nicu-Cătălin Drăghici, Octavia Sălăgean, Mircea-Vasile Milaciu, Olga-Hilda Orășan, Călin-Vasile Vlad, Irina-Maria Vlad, Teodora Alexescu, Ioana Para, Simina-Felicia Țărmure, Elisabeta-Ioana Hirișcău and Gabriela-Bombonica Dogaru
Int. J. Mol. Sci. 2024, 25(20), 10909; https://doi.org/10.3390/ijms252010909 - 10 Oct 2024
Viewed by 1255
Abstract
Multiple sclerosis (MS) is an immune-mediated disease characterized by inflammation, demyelination, and neurodegeneration within the central nervous system. Brain plasticity, the brain’s ability to adapt its structure and function, plays a crucial role in mitigating MS’s impact. This paper explores the potential benefits [...] Read more.
Multiple sclerosis (MS) is an immune-mediated disease characterized by inflammation, demyelination, and neurodegeneration within the central nervous system. Brain plasticity, the brain’s ability to adapt its structure and function, plays a crucial role in mitigating MS’s impact. This paper explores the potential benefits of lifestyle changes and nutraceuticals on brain plasticity in the MS population. Lifestyle modifications, including physical activity and dietary adjustments, can enhance brain plasticity by upregulating neurotrophic factors, promoting synaptogenesis, and reducing oxidative stress. Nutraceuticals, such as vitamin D, omega-3 fatty acids, and antioxidants like alpha lipoic acid, have shown promise in supporting brain health through anti-inflammatory and neuroprotective mechanisms. Regular physical activity has been linked to increased levels of brain-derived neurotrophic factor and improved cognitive function. Dietary interventions, including caloric restriction and the intake of polyphenols, can also positively influence brain plasticity. Integrating these lifestyle changes and nutraceuticals into the management of MS can provide a complementary approach to traditional therapies, potentially improving neurological outcomes and enhancing the quality of life for the MS population. Full article
(This article belongs to the Special Issue Advances in Nutritional Approach to the Neurodegenerative Diseases)
Show Figures

Figure 1

Back to TopTop