MYC and p53 Gene Families
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 3720
Special Issue Editor
Interests: neuroblastoma; brain tumor; transcriptional regulation; gene evolution; de novo gene; long non-coding RNA; p53 family members; MYC family members
Special Issue Information
Dear Colleagues,
MYC and p53 are a representative oncogene and tumor suppressor gene, respectively. Both genes comprise a family of genes and the two families regulate each other's functions in cancer, resulting in a fierce competition between tumor promotion and suppression. The two gene families regulate each other directly and indirectly not only in cancer, but also in development and ageing, influencing the phenotype of the individual throughout life. This special issue calls for original articles and reviews focusing on the biological roles of the p53 and MYC gene families.
The following are examples of research topics of interest; however, any related studies regarding the biological roles of the p53 gene family (p53, p63, and p73) and MYC gene family (MYC, MYCN, and MYCL) will be considered.
- The role of the p53 family of genes (p53, p63, and p73) or their downstream target genes in cancer, development, and ageing.
- The role of MYC family of genes (MYC, MYCN, and MYCL) or their downstream target genes in cancer, development, and ageing.
- Inter-regulatory relationship between members of the p53 and MYC gene families.
- Evolutionary studies on the p53 or MYC gene families.
Dr. Yusuke Suenaga
Guest Editor
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