Liquid Biopsy in the Approach of Non-communicable Chronic Diseases (NCCD) and Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 3619
Special Issue Editor
Special Issue Information
Dear Colleagues,
Liquid biopsy refers to a non-invasive diagnostic technique that involves the detection and analysis of biomarkers, such as circulating tumor DNA (ctDNA), circulating RNA (cRNA), circulating tumor cells (CTCs), and exosomes, in liquid biological samples such as blood, urine, tears and saliva. Liquid biopsy is thus a new tool in understanding the mechanisms of health and disease, advising the precision medicine field. The technique has gained significant attention in recent years, particularly in the field of oncology, for its potential to detect cancer at an early stage, monitor treatment response, and predict disease recurrence. This approach aims to provide greater accuracy in its diagnosis, with the least possible discomfort to the patient at the time of collection and also complement and/or replace tissue biopsy. The application of liquid biopsy can also serve to outline strategies in the complications of chronic non-transmissible diseases. Worldwide, premature mortality from chronic non-communicable diseases (NCDs) accounted for approximately 44% of all deaths caused by these diseases, data that show the impact of this group of diseases on patients aged 30 to 69 years. Predicting, evaluating and providing conditions for decision-making based on biomarkers obtained by liquid biopsy in easily obtainable biological matrices can be a new way to contribute in the laboratory to early diagnosis and also to outline strategies for the promotion and prevention of future damage and early deaths. Therefore, we invite you to contribute to this Special Issue, which aims to show the use of different biological matrices, new physical–chemical methods applied to detect markers and even new approaches to established markers for chronic non-transmissible diseases and cancer. Pre-clinical and clinical studies will be evaluated for the aforementioned purpose.
Dr. Fernando Luiz Affonso Fonseca
Guest Editor
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Keywords
- biomarkers
- alternative biological matrices
- laboratory nethods
- precision medicine
- liquid biopsy
- cancer
- non-communicable chronic diseases
- clinical studies
- preclinical studies
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