Advances in Brain Arteriovenous Malformation Research
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (31 July 2019) | Viewed by 6426
Special Issue Editors
Interests: neurovascular diseases; cerebrovascular diseases; cardiovascular diseases; brain AVMs; angiogenesis; vascular inflammation; thrombosis
Special Issues, Collections and Topics in MDPI journals
Interests: cerebrovascular diseases; brain AVMs; brain aneurysms; cerebral cavernous angiomas; angiogenesis
Special Issue Information
Dear Colleagues,
Arteriovenous malformations (AVMs) are tangles of dysplastic vessels fed by arteries and drained by veins without intervening capillaries, forming a high-flow, low-resistance shunt between the arterial and venous systems. Recent findings from animal models and genetic studies suggest that brain AVMs, which were long considered congenital, arise from aberrant vasculogenesis and/or angiogenesis, probably upon subclinical injuries of the brain in predisposed individuals. In this Special Issue, we will publish articles focused on recent advances in the pathophysiology of brain AVMs. Preference will be given to original research articles on the genetic, epigenetic, and molecular mechanisms underlying AVM formation, including, but not limited to, the role of aberrant angiogenesis and vasculogenesis, angiogenic growth factors, and inflammation. Studies using animal models and innovative experimental techniques will also be welcome. We will also accept articles on recent advances in the diagnosis and therapy of brain AVMs, such as studies on novel imaging strategies, anti-angiogenic treatments, and robot-assisted surgery. Outstanding reviews and meta-analysis will also be considered.
Assoc. Prof. Roberto Pola
Dr. Carmelo Lucio Sturiale
Guest Editors
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Keywords
- brain arteriovenous malformation
- angiogenesis
- vasculogenesis
- animal models
- gene -expression
- GWAS
- inflammation
- growth factors
- hemorrhagic risk
- diagnosis
- therapy
- review
- meta-analysis
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