Curcumin Derivatives and Curcuminoids as Theranostic Agents in Alzheimer’s Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 10588
Special Issue Editor
Interests: synthesis and biological studies on anti-inflammatory and antioxidant agents, on inhibitors of enzymes implicated in the inflammation and in the coagulation process in general; correlation of inflammation with cancer; neurodegeneration; antioxidant activity; theoretical and experimental calculation of physicochemical parameters implicated in biological response; use of computational chemistry in drug design as well as bioactive compounds of natural origin, e.g., essential oils
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Special Issue Information
Dear Colleagues,
Curcumin, curcumin analogues, derivatives, and curcuminoids exert several biological activities, including certain interesting therapeutic properties against Alzheimer's disease (AD). Alzheimer’s disease is the most common neurodegenerative disease influencing the elderly population globally. At present, the therapeutic agents available do not offer a satisfactory cure to and/or treatment for AD. During the last decade, the scientific community has been focused on research into more efficient drugs to face neurological disorders. Furthermore, there is a need for more precise and accurate diagnostic agents. From this point of view, the invention of theranostic agents (both diagnostic and therapeutic) for neurodegenerative diseases will be of great significance, and the curcumin scaffold, which has been found to be a unique structure for a 2nd-generation Aβ PET tracer development, has the potential to play an important role in this.
This Special Issue, “Curcumin derivatives and Curcuminoids as Theranostic agents in Alzheimer’s Disease”, of the International Journal of Molecular Sciences will comprise a selection of research papers and reviews offering knowledge on the design, synthesis, development, properties and special structural characteristics of curcumin derivatives and curcuminoids as theranostic agents (both therapeutic and diagnostic), new entities inserted in clinical applications, in vitro and in vivo studies, strategies and identification of the key biological processes in which these agents will be implicated.
Prof. Dr. Dimitra Hadjipavlou-Litina
Guest Editor
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Keywords
- Curcumin derivatives
- Curcuminoids
- Theranostic agents
- Neurological disorders
- Alzheimer
- Complexes
- Design
- Synthesis
- Development
- PET
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