Mechanism and Regulation of Pre-mRNA Splicing: 3rd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 1997
Special Issue Editor
Interests: pre-mRNA splicing; mechanism of splicing; regulation of splicing; aberrant splicing in diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In eukaryotes, most gene transcripts or pre-mRNAs are interrupted by intervening sequences termed introns, which are precisely removed by a process called splicing. This process is essential since spliced mRNAs serve as templates for proteins. Regulation in the splicing process is certainly crucial for a wide variety of biological and physiological phenomena. The process is therefore highly discriminatory and faithful, and mis-regulation in this process causes disorders in cell functions, often with severe clinical consequences.
This Special Issue will cover, but is not limited to, the following topics:
- The mechanism and regulation of constitutive and alternative splicing;
- The mechanism and regulation of splicing-linked post-splicing processes;
- Pre-mRNA–protein interactions involved in splicing and splicing-linked processes;
- hnRNP/mRNP assembly and functions in splicing and splicing-linked processes;
- Evolutional studies of pre-mRNAs and splicing;
- Pre-mRNA processing in development and diseases including cancers.
Prof. Dr. Akila Mayeda
Guest Editor
Manuscript Submission Information
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Keywords
- pre-mRNA Splicing
- splicing
- mechanism of splicing
- regulation of splicing
- aberrant splicing in diseases
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