Advances in Neurodegenerative Diseases and Inflammation: Pathogenesis, Biomarkers and Treatments
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 2901
Special Issue Editors
Interests: biomarkers; neurodegenerative diseases; Alzheimer's disease; multiple sclerosis; vitamin D; neurodegeneration; Parkinson’s disease; laboratory medicine
Special Issues, Collections and Topics in MDPI journals
Interests: neurological disorders; biomarkers; ischemic stroke; multiple sclerosis; synaptic dysfunction; exosomal miRNAs; DNA binding protein; Alzheimer’s disease
Special Issue Information
Dear Colleagues,
Neurodegenerative diseases (ND) are a heterogeneous group of disorders characterized by the progressive dysfunction and loss of neurons in different areas of the central or peripheral nervous system. NDs represent a big challenge for scientific research due to their prevalence, cost and unknown pathophysiological mechanisms and the lack of mechanism-based treatments.
An ND patient’s care pathway, from screening to diagnosis, prognosis and monitoring, is complex and relies mainly on clinical criteria. However, especially in the early stages, NDs have overlapping signs and symptoms leading to delayed diagnosis. Thus, tools are urgently needed to support clinicians in the early and appropriate management of NDs. In recent decades, significant advances have been made, but further efforts are mandatory in the field of ND research.
This Special Issue aims to collect research articles and literature reviews in the field of ND research, including Dementia, Multiple Sclerosis, Amyotrophic Lateral Sclerosis and Parkinson’s disease, to unravel molecular mechanisms underpinning their pathogeneses and new molecular biomarkers, with a focus on the role of inflammation. Indeed, in recent decades, evidence from several studies supports the pivotal role of inflammation in ND pathogenesis.
Dr. Luisa Agnello
Dr. Anna Maria Ciaccio
Guest Editors
Manuscript Submission Information
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Keywords
- neurodegeneration
- inflammation
- biomarkers
- Alzheimer’s disease
- molecular mechanism
- pathogenesis
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