Genomics and Proteomics of Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 April 2025 | Viewed by 2148
Special Issue Editor
Interests: cancer cell proteomic profile; new anticancer therapy; cancer related signaling pathways
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Carcinogenesis, tumor growth, and cancer progression are classified as complex multifactorial tissue-dependent processes. Furthermore, tumor growth and progression are primarily stimulated by genetic predispositions or environmental causes, or a combination of the two. Genetic and epigenetic modifications are important in many diseases, especially in cancer development where cells are able to proliferate and escape the mechanisms that normally control their survival and migration. Cancer cells show extensive alterations in protein expression levels and in protein phosphorylation. A complete characterization of the altered proteins in cancer versus normal cells can also help explain multidrug resistance, therapy-related side effects, and disease recurrence after therapy. Proteomic profile data can be used to elucidate cancer biology and metastasis processes in detail and drive the development of novel drug targets.
This Special Issue of IJMS focuses on the proteins involved in the signaling pathways implicated in cancer biogenesis and progress.
Dr. Raffaella Lazzarini
Guest Editor
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Keywords
- cancer
- carcinogenesis
- genetic
- epigenetic modification
- protein expression
- protein phosphorylation
- proteomic
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