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Advances in Solution Blow Spinning Methods for Pharmaceutical and Biomedical Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 3128

Special Issue Editors


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Guest Editor
1. Department of Chemistry, School of Science, Universidad de Navarra, 31080 Pamplona, Spain
2. SUMBET (Supramolecular Materials for Biomedical and Environmental Technologies), Universidad de Navarra, C/ Irunlarrea 1, 31080 Pamplona, Spain
3. BIOMA (Instituto de Biodiversidad y Medioambiente), Universidad de Navarra, C/ Irunlarrea 1, 31080 Pamplona, Spain
Interests: supramolecular chemistry; cyclodextrins; colloids; polymers; hydrogels; nanocomposites; scattering methods
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Guest Editor
Department of Materials Science and Engineering and Chemical Engineering, Instituto de Química y Materiales Álvaro Alonso Barba (IQMAA), Universidad Carlos III de Madrid, Leganés, 28911 Madrid, Spain
Interests: design, preparation, and characterization of polymer-based multifunctional materials with (i) special electrical properties and (ii) antibacterial activity; characterization of polymers and composite materials; use of fluorescent probes and labels to monitor physico-chemical changes at a molecular scale; atomic force microscopy: nanothermodeformation (linear coefficients of thermal expansion of polymer thin films), nanopiezodeformación; FTIR (middle and near range): structural, dynamics, and aging phenomena studies; solution blow spinning
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Department of Materials Science and Engineering and Chemical engineering and Instituto Tecnológico de Química y Materiales "Álvaro Alonso Barba", Universidad Carlos III de Madrid, Avda. Universidad 30, 28911 Leganés, Spain
Interests: textiles; fiber; textile engineering; materials chemistry; antimicrobials materials; natural fibers; material characterization; polymers surface modification
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Special Issue Information

Dear Colleagues,

As guest editors, we are pleased to invite you to contribute to a new Special Issue entitled “Advances in Solution Blow Spinning Methods for Pharmaceutical and Biomedical Applications”.

In recent years, Solution Blow Spinning (SBS) is emerging as a new technology for the production of polymeric, nanocomposite and ceramic materials in the form of nano and microfibers, with similar features to those attained by other procedures, like electrospinning, melt blowing or wet spinning. The key advantages of SBS over other methods are the fast generation of fibers and the possibility of their on-site generation. While producing a large number of non-woven nanofibers in the shortest time is a crucial factor in large-scale manufacturing, the in-situ generation of the material in the form of sprayable, multifunctional dressings capable of releasing embedded active agents on a wounded tissue, or its use in operation theatres to prevent haemostasis during surgical interventions, amongst other applications, open a wide range of possibilities. The interest for this spinning technology is evident from the growing number of patents and articles published over the last few years.

In this Special Issue, original research articles are welcome. Research areas may include (but are not limited to) the following:

  • Proof of concept investigations and beyond on blow spun-based fibers for drug delivery applications.
  • Production of blow spun-based materials for minimally invasive surgery.
  • In-vitro and in-vivo-testing of materials produced by solution blow spinning and design of ad hoc protocols for these systems.
  • Naconocomposites produced by solution blow spinning for biomedical applications.
  • Design of solution blow spinning instrumentation for on-site and off-site fibers production.
  • Optimisation of solution blow spinning set-ups for the production of micro and nanofibers.
  • Investigations on solvent-polymer compatibility for solution blow spinning applications.

Researchers are also encouraged to submit articles or reviews that may explore and help extend the solution blow spinning technology to fields other than Pharmacy and biomedicine.

We look forward to receiving your contributions.

Prof. Dr. Gustavo González-Gaitano
Prof. Dr. Javier González-Benito
Dr. Ana Kramar
Guest Editors

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Keywords

  • solution blow spinning
  • microfibers
  • nanofibers
  • nonwovens
  • nanocomposites
  • biodegradable polymers
  • biomaterials
  • transdermal delivery
  • antimicrobial wound dressings
  • wound healing
  • minimally invasive surgery

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Published Papers (1 paper)

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Review

24 pages, 3007 KiB  
Review
Advances in Biomedical Applications of Solution Blow Spinning
by Javier Carriles, Paul Nguewa and Gustavo González-Gaitano
Int. J. Mol. Sci. 2023, 24(19), 14757; https://doi.org/10.3390/ijms241914757 - 29 Sep 2023
Cited by 11 | Viewed by 2596
Abstract
In recent years, Solution Blow Spinning (SBS) has emerged as a new technology for the production of polymeric, nanocomposite, and ceramic materials in the form of nano and microfibers, with similar features to those achieved by other procedures. The advantages of SBS over [...] Read more.
In recent years, Solution Blow Spinning (SBS) has emerged as a new technology for the production of polymeric, nanocomposite, and ceramic materials in the form of nano and microfibers, with similar features to those achieved by other procedures. The advantages of SBS over other spinning methods are the fast generation of fibers and the simplicity of the experimental setup that opens up the possibility of their on-site production. While producing a large number of nanofibers in a short time is a crucial factor in large-scale manufacturing, in situ generation, for example, in the form of sprayable, multifunctional dressings, capable of releasing embedded active agents on wounded tissue, or their use in operating rooms to prevent hemostasis during surgical interventions, open a wide range of possibilities. The interest in this spinning technology is evident from the growing number of patents issued and articles published over the last few years. Our focus in this review is on the biomedicine-oriented applications of SBS for the production of nanofibers based on the collection of the most relevant scientific papers published to date. Drug delivery, 3D culturing, regenerative medicine, and fabrication of biosensors are some of the areas in which SBS has been explored, most frequently at the proof-of-concept level. The promising results obtained demonstrate the potential of this technology in the biomedical and pharmaceutical fields. Full article
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