Molecular Advances in Endocrine Toxicity
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".
Deadline for manuscript submissions: closed (15 July 2023) | Viewed by 8374
Special Issue Editor
Special Issue Information
Dear Colleagues,
Endocrine toxicity presents a major risk for growth retardation, suppressed development, infertility, altered blood pressure, altered ion concentrations, and other substances in the blood and even behavior. Endocrine toxicity is a multifactorial disorder involving altered functions of the hypothalamus, pituitary gland, thyroid, parathyroid, adrenal gland, gonads, placenta, pancreas, and even the kidney and gastrointestinal tract. This toxicity involves interference in the synthesis, secretion, transport, metabolism, and binding action necessary for the maintenance of homeostasis. Such interference ultimately results in loss of normal tissue function, development, growth, or reproduction. Unregulated factors that contribute to congenital disorders and autoimmune response contribute to altering endocrine milieu and the onset of diseases such as cancer, metabolic disorders, and infertility. Therefore, unraveling the underlying causes of endocrine toxicity is critical to improving disease burden. Oxidative stress resulting from accumulation of reactive radicals and subsequent inflammation contributes significantly to the pathogenesis of endocrine toxicity. Thus, remediating specific sources of oxidative stress inducers can improve endocrine-regulated growth and development, metabolism, blood pressure, and infertility in affected subjects. The topic of endocrine toxicity is an alphabet soup for numerous factors that initiate and maintain the condition.
Therefore, in this Special Issue, we will discuss the role of environmental pollutants/endocrine disruptors in the mechanisms associated with the generation of oxidative stress and their role in metabolic dysregulation and inflammation. Further, we will describe the potential interventions that target specific oxidative stress and metabolic pathways that can restore homeostasis.
Dr. Anthony Archibong
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- environment
- toxicity
- endocrine disruptors
- metabolism
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
