Molecular and Cellular Mechanisms of Corneal Fibrosis/Scarring and Advances in Therapy 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 1602
Special Issue Editors
Interests: complex ocular surface disorders (graft versus host disease, Stevens Johnson syndrome, cicatricial disorders); keratoconus; other corneal ectasias and collagen crosslinking; corneal infections; corneal transplantation; corneal imaging
2. Eye-Academic Clinical Program, Duke-National University of Singapore (NUS) Graduate Medical School, Singapore 169857, Singapore
Interests: cornea cell biology; cell culture
Special Issues, Collections and Topics in MDPI journals
Interests: perforating and lamellar corneal transplantation; ocular surface diseases; cataract; glaucoma; corneal stromal diseases; corneal tissue engineering; corneal wound healing
Special Issue Information
Dear Colleagues,
This Special Issue is a continuation of our previous Special Issue, “Molecular and Cellular Mechanisms of Corneal Fibrosis/Scarring and Advances in Therapy”.
Corneal blindness is a leading cause of vision loss. The cornea is susceptible to injury by external agents. Typical corneal injuries include trauma, thermal/chemical burns, and infection. The wound healing response results in a deposition of disorganized and fibrotic extracellular matrices (ECMs), contributing to corneal scarring that impedes vision. While the only treatment option is the replacement of damaged corneas through transplantation using cadaveric donor corneas, the global shortage of donor tissues and the sustainability of this option amidst a growing aging population is of utmost concern. This Special Issue of IJMS aims to provide an overview of the molecular and cellular mechanisms associated with corneal fibrosis and scarring, as well as the latest research on the treatment modalities of corneal scarring and their short- and long-term consequences. This will be of interest to scientists and clinicians working to fight against corneal blindness. This Special Issue will consider reviews and original research manuscripts on topics including (but not limited to): the underlying mechanisms of stromal wound healing and ECM remodeling, diagnostics/prognostics, and new insights into treatment modalities associated with fibrosis and scar management (such as early wound intervention and cell-based and cell-free strategies).
Prof. Dr. Vishal Jhanji
Dr. Gary Hin-Fai Yam
Dr. Matthias Fuest
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- corneal injury
- corneal diseases
- fibrosis
- scarring
- basic research
- clinical research
- animal models
- pathophysiology
- diagnosis
- treatment
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
