New Advances of the Molecular Mechanisms of Gonad Development, Gametogenesis, and Fertilization
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 March 2025 | Viewed by 1591
Special Issue Editor
Interests: sperm-egg binding (cellular recognition); sperm penetration through the egg envelope; alteration of the egg envelope by components of the egg cortical granules to effect a block to polyspermy; modification of the egg envelope to protect and regulate the environment for the developing embryo
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Special Issue Information
Dear Colleagues,
The molecular mechanisms of gonad development and fertilization have been studied for many years using different species. Since Chiquoine identified mammalian primordial germ cells (PGCs) in 1954, the molecular mechanisms of germline establishment via embryogenic gonad development have been investigated. Investigations have focused on the roles of PGCs using many different species. As a result of these efforts, knowledge of the molecular mechanisms of gonad development during embryogenesis, oogenesis and spermatogenesis in the developing ovary and testis, and fertilization has increased. However, research in these areas is still fragmented and/or limited for many animal species. To provide an integrated view of gonad development and fertilization and to further elucidate the cellular and molecular mechanisms of gonad development and sperm-egg interactions (fertilization), authors are invited to submit manuscripts that will advance knowledge in the field of reproduction. Such knowledge may be applied to human reproduction and agricultural species and used to protect endangered species worldwide. Basic research on the cellular and molecular mechanisms of gonad development, fertilization, and early development through hatching in invertebrate and vertebrate animals is applicable.
Dr. Kenji Murata
Guest Editor
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Keywords
- primordial germ cells
- sex differentiation
- extensive epigenetic reprogramming
- Fertilization
- oogenesis
- spermatogenesis
- vertebrate
- imvertebrate
- Sperm-egg interaction
- folliculogenesis
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