Extracellular Vesicles in Cancer Prevention and Treatment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 350
Special Issue Editors
Interests: cancer; cancer target therapy; nutraceutics; cancer vaccines; extracellular vesicles; biomarkers; ultrastructural pathology
Special Issues, Collections and Topics in MDPI journals
Interests: anticancer; polyphenols; cancer nutraceutical and immunotherapy; natural compounds on cancer cell growth
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cell-derived extracellular vesicles (EVs) have attracted attention in recent years. EVs are micro- or nano-sized membrane vesicles secreted from different cell types, including immune/inflammatory, mesenchymal, endothelial, and cancer cells. EVs participate in intercellular communication and contain different active cargos, including proteins, RNA, miRNAs, and DNA, that modulate cellular behavior. EVs regulate several cellular processes, modifying tissue microenvironments, and inducing angiogenesis, invasion, progression, and metastasis during cancer development. Moreover, EVs can be isolated from biological fluids, such as blood plasma, serum, saliva, and urine. Accordingly, EVs are promising biomarkers candidates for the prevention, early diagnosis, and follow-up of cancer patients. The opportunity to incorporate active biomolecules, nucleic acids, and drugs into EVs in conjunction with the capability of EVs to overcome natural barriers and with their cell-targeting properties could render the EVs effective therapeutic tools for cancer therapy.
This Special Issue will focus on the use of EVs as preventive or therapeutic tools in cancer. The authors are invited to contribute with a review or full research paper for peer review to this Special Issue.
Dr. Laura Masuelli
Prof. Dr. Roberto Bei
Guest Editors
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Keywords
- extracellular vesicles
- biomarkers
- cancer
- prevention
- therapy
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