Targeted Nanoparticles and Specific Cell Targeting Strategies for Chronic Liver Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 3886
Special Issue Editor
Interests: alcoholic liver injury; non-alcoholic fatty liver; steatohepatitis; nanoparticle; fibrosis; Kupffer cell; macorphage; senescence; muscle regeneration; cancer; diagnostic marker
Special Issue Information
Dear Colleagues,
Various nanoparticles have recently emerged and been widely applied in drug delivery, nanomedicine, advanced diagnostic imaging fields, and cancer therapy. Nanoparticles have several merits in terms of cell-specific targeting due to their applicable nanoscale sizes. The liver is one of the most important immune organs encountering several exogenous materials entering the human body system, which means that it is also one of main target organs for nanoparticle application for treatment or diagnosis. Cell-specific targeting through nanoparticle modification is a promising strategy to treat chronic liver disease, and various target cells can be effective depending on the liver disease stage. Therefore, cell-specific targeting strategies such as liver Kupffer cells, neutrophils, sinusoidal vessel endothelial cells, hepatic stellate cells, and hepatocytes are essential to modulate various therapeutic targets in chronic liver disease as well as in liver cancer. This Special Issue welcomes any original research and reviews related to various cell specific targeting strategies, modifications, characterizations of novel nanoparticles to target various liver cells as well as modulation of various therapeutic targets using nanoparticle-based delivery systems for chronic liver disease and liver cancer.
Dr. Jin-Kyu Park
Guest Editor
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Keywords
- nanomedicine
- nanoparticle-based gene delivery
- nanoparticle-based drug delivery
- cell-targeted nanoparticle
- nanoparticle modification
- chronic liver disease
- Kupffer cell
- liver cell
- cell-specific targeting
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