Mechanisms of Immune Tolerance and Autoimmune Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 20 May 2025 | Viewed by 5489
Special Issue Editors
2. Immunology Department, Marqués de Valdecilla University Hospital, 39008 Santander, Spain
3. Molecular Biology Department, University of Cantabria, 39011 Santander, Spain
4. National Microbiology Center, National Institute of Health Carlos III, 28220 Madrid, Spain
5. Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
Interests: immunology; autoimmunity; transplantation; tolerance; human pathology; biomarkers
Special Issues, Collections and Topics in MDPI journals
Interests: trained immunity; immune tolerance; organ transplantation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The field of immunological tolerance and the induction of autoimmune diseases has started focusing on the role of the adaptative immune response and how the failure of central and peripheral tolerance could induce autoimmunity. In the last decade, increasing attention has been paid to the ways in which innate immunity and the cellular participants in inflammation might be implicated in these diseases. Therefore, several new autoinflammatory diseases have been described using the genetic data associated with functional consequences. Through the study of the genetic, phenotypic, metabolic and functional mechanisms involved in these immune-mediated diseases, novel diagnostic and therapeutic approaches have been developed. Furthermore, there is continuum with no clear border between autoinflammatory and autoimmune disease. This Special Issue specifically welcomes the submission of studies that focus on the basic mechanisms underlying the production of autoimmune and autoinflammatory diseases, in addition to translational studies.
Prof. Dr. Marcos López Hoyos
Dr. Jordi Ochando
Guest Editors
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Keywords
- immunological tolerance
- autoimmune diseases
- autoinflammatory diseases
- inflammation
- immune-mediated diseases
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