Molecular Biological Insights and Targeted Therapies for Sarcomas
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 December 2024 | Viewed by 1544
Special Issue Editor
Interests: cancer biology; sarcoma; IGF system; RNA-binding proteins; drug resistance; cell cultures
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Despite the rarity and heterogeneity of sarcoma, current intensive chemotherapy and surgical procedures are able to significanly ameliorate the survival of patients with localized disease. On the contrary, metastatic disease remains a major challenge. Breakthroughs in genomic sequencing techniques, coupled with advances in experimental models, have improved our knowledge of the mechanisms of progression and metastasis of sarcomas. These approaches hold the promise to benefits the development of novel targeted therapies and personalized treatment for sarcoma patients.
This Special Issue aims to provide new impetus to molecular and personalized medicine development for sarcomas. We are eager to publish original research as well as reviews on molecular biology, mechanisms of metastases, microenvironment, and cutting-edge treatments for bone and soft-tissue sarcomas—including discussions of epigenetics, genetics, signaling pathways, and immunotherapies. Reports on new combination therapies and novel preclinical models are also welcome.
Dr. Caterina Mancarella
Guest Editor
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Keywords
- sarcoma
- therapeutic target
- preclinical models
- molecular target
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