Platelets at the Intersection of Atherosclerosis Processes
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 15
Special Issue Editor
Interests: dental biochemistry; oxidative stress in systemic and oral diseases; salivary biomarkers; AKT/mTOR signaling pathway; molecular and biochemical aspects in burns
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Atherosclerosis begins with injury to the endothelium caused by factors such as high blood pressure, diabetes, smoking, and high levels of LDL cholesterol. Platelets react by attaching to the injured endothelium, releasing chemokines and adhesion molecules which activate immune cells and intensify inflammation. This interaction attracts immune cells to form plaques, especially in areas of shear stress, where proteins like platelet–endothelial cell adhesion molecule-1 (PECAM-1) strengthen the adhesion between platelets and endothelial cells. Additionally, platelets contribute to inflammation by forming aggregates with leukocytes and increasing vascular permeability. Platelets serve as key players in the complex interplay of factors that drives atherosclerosis, making them a critical target for therapeutic strategies aimed at reducing cardiovascular risk.
This Special Issue is supervised by Prof. Dr. Maria Greabu and assisted by our Topical Advisory Panel Member Dr. Bogdana Virgolici (University of Medicine and Pharmacy).
Prof. Dr. Maria Greabu
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- platelets
- inflammation
- atherosclerosis
- endothelial cells
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
