RNA Dysregulation in Human Diseases: from Basic to Translational Applications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 3643
Special Issue Editor
2. Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang 10408, Korea
Interests: RNA-binding proteins; RNA modifiers; oncogenic RNAs; noncoding RNA; miRNAs; posttranscriptional regulation; cancer
Special Issue Information
Dear Colleagues,
RNA molecules undergo multiple posttranscriptional processes for gene expression regulation in eukaryotes, including RNA splicing, transport, localization, stability, translation, and degradation. Recent reports have shown various examples of the dysregulation of RNA-linked biological processes in major human diseases. This Special Issue aims to understand, diagnose, and develop therapeutic approaches for the regulation of RNA-mediated biological processes during tumorigenesis, development of genetic disorder, and RNA virus infection in humans.
This issue will handle the following RNA-related research areas:
- Role of RNA post-transcriptional regulome (RNA-binding proteins, RNA modifiers, and modulatory RNAs) in cancer, and their molecular interplay with microRNAs and other oncogenic RNAs;
- Molecular interplay between host cellular RNA regulome and RNA viruses during the virus-mediated pathogenesis in humans;
- Molecular interplay between RNA and RNA regulome for the dysregulation of splicing in human diseases;
- Diagnostic application of microRNA, development of microRNA-sensing system, and its translational application in cancer;
- Extracellular small noncoding RNA in cancer malignancy; basic, diagnostic and translational applications.
Prof. Dr. Jong Heon Kim
Guest Editor
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Keywords
- Post-transcriptional regulation;
- RNA-binding proteins;
- RNA modifiers;
- Noncoding RNAs;
- MicroRNAs;
- Cancer;
- Oncogenic RNAs;
- Regulation of splicing;
- RNA viruses;
- Extracellular small noncoding RNAs.
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