Biomarkers for Diagnosis and Prognosis in Urological Tumors II
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (31 January 2023) | Viewed by 5520
Special Issue Editor
Interests: prostate cancer; diagnosis; oncology; statistic; R project for statistical computing; biomarker
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
When a tumor is diagnosed, many patients are faced with the question of how long they will survive with this condition and how and how fast they have to be treated. Clinical and pathological examinations help to differentiate tumors in terms of their degree of aggressiveness. This may help to make a treatment decision after a tumor diagnosis and to estimate cancer-specific survival. However, individual risk stratification is also subject to some challenges. For example, it is not always possible to find the relevant tumor site in a biopsy, or it is difficult to reach it. Pathological examination can also be interobserver-variable. An example of this is Gleason grading in prostate cancer. In many cases, urological tumors present a heterogeneity that cannot be precisely determined. Therefore, it may happen that tumors which do not differ in their clinical and pathological characteristics have to be treated a different way or have a completely different oncological outcome after treatment.
Genetic analyses may be able to answer these clinical questions. Various methodologies can be used for this purpose. These investigations may involve tumor tissue, adjacent stroma tissue, and urine or blood samples.
For this Special Issue, we are looking for original research article and state-of-the-art reviews which can demonstrate that new or already established genetic markers may be helpful to improve diagnosis or better predict oncological outcome.
Dr. Pierre Tennstedt
Guest Editor
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