Recent Advances in Systems Metabolic Engineering Strategies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (30 September 2024) | Viewed by 10876
Special Issue Editor
Interests: synthetic biology; enzyme engineering; metabolic engineering; natural products; microbiome engineering
Special Issue Information
Dear Colleagues,
As a result of the ongoing climate crisis, there is growing interest in producing industrially important chemicals and materials from non-edible renewable resources or carbon dioxide instead of relying on traditional petrochemical refinery processes. Systems metabolic engineering, which integrates traditional metabolic engineering principles with modern technologies including synthetic biology, evolutionary engineering, and systems biology, has been playing a crucial role in constructing efficient microbial cell factories capable of industrially producing chemicals and materials. The field is rapidly advancing with the emergence of cutting-edge computational techniques, including genome-scale metabolic modeling, artificial-intelligence-based strain design, and computational enzyme design.
This Special Issue focuses on the recent tools and strategies for systems metabolic engineering. Original articles with significant advancements in the field and review papers that provide useful insights are both welcome. Potential topics include, but are not limited to, omics analysis, enzyme evolution, in silico pathway prediction and design, genome engineering, genome-scale metabolic modelling, natural-product biosynthesis, and fermentation techniques.
Dr. Dongsoo Yang
Guest Editor
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Keywords
- systems metabolic engineering
- synthetic biology
- genome-scale metabolic modeling
- microbial cell factory
- enzyme engineering
- metabolic pathway design
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