New Insights for Medicinal Chemical Approaches to Fighting Viruses
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 5271
Special Issue Editor
Interests: anticancer agents; targeted delivery; analytics; medicinal chemistry; ADME/DMPK
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the last ten years, globalization, global warming, and population aging have contributed to the spread of emerging or re-emerging viruses such as SARS-CoV-2, West Nile, Dengue, Zika, Ebola and, recently, monkeypox virus. The number of reported cases is impressive, and considering that many viral infections occur asymptomatically it is conceivable that numbers will increase significantly in the coming years.
With the risk of new epidemics just around the corner, there is an urgent need to find new antivirals that are able to counter future epidemics. Antivirals can be designed using computational methods, rational drug design, or high-throughput screening, or by finding novel uses for already-developed compounds (drug repurposing).
This Special Issue of IJMS will focus on advances in the field of antiviral therapy, including the development of novel antivirals, drug-repurposing approaches, mechanism of action elucidation, sustainable procedures to scale up the synthesis of existing antivirals, and optimization of ADME and PK properties. We welcome the submission of papers focusing on the development of antivirals using cutting-edge technologies such as proteolysis-targeting chimeras (PROTACs) and ribonuclease-targeting chimeras (RIBOTACs).
Dr. Elena Dreassi
Guest Editor
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Keywords
- antivirals
- mechanism of action
- PROTACs
- RIBOTACs
- ADME
- PK
- medicinal chemistry
- viruses
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