Advances in Head and Neck and Skin Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 5759
Special Issue Editors
Interests: head and neck cancer and skin cancer; squamous cell carcinoma; cancer
Special Issues, Collections and Topics in MDPI journals
Interests: melanoma; dermatology; dermatoscopy; hidradenitis suppurativa; acne
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Immunotherapy and a combination of old and new treatments have revolutionized the scenario of head and neck and skin cancers. The aging of populations justifies the growing number of patients who deserve a multidisciplinary approach. In head and neck cancer, despite chemoradiotherapy, about 50% of patients with locally advanced disease will recur in 5 years, and in recurrent metastatic disease, the prognosis, even if patients are treated with immunotherapy or chemo-immunotherapy is dismal, only 20% of responders benefit from these new treatments. Melanoma is the neoplasm that has paved the way for innovations in molecular biology and immunotherapy, and the field of study is always in turmoil to further increase the outcomes. Basal cell carcinoma (BCC) is the most frequent among nonmelanoma skin carcinomas. Hedgehog inhibitors have changed the scenario in BCC, and second-line treatment is now available for incompliant or progressive disease. In squamous cell carcinoma, an increasing number of elderly is now a candidate for immunotherapy with Cemiplimab. Interestingly, new combinations with anti-epidermal growth factor receptor antibodies and other tyrosine kinase inhibitors are ongoing, and promising results are awaited. Most nonmelanoma skin cancer affects the head and neck region.
Continuing education and a very compact multidisciplinary group are essential to ensure high levels of procedures and cures. Every physician should contribute with the last significant advance in their field.
The scope of this Special Issue is to collect recent advances in head and neck cancer and skin cancer treatments.
Dr. Nerina Denaro
Prof. Dr. Gianluca Nazzaro
Dr. Iorio Giuseppe Carlo
Guest Editors
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Keywords
- head and neck cancer
- melanoma
- nonmelanoma skin cancer
- immunotherapy
- tumor microenvironment
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