Molecular and Cellular Mechanisms of Spinal Cord Injury and Repair
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 25 April 2025 | Viewed by 1678
Special Issue Editor
Special Issue Information
Dear Colleagues,
Spinal cord injury (SCI) is a devastating, debilitating, and life-altering condition that currently lacks a cure or effective treatment. After SCI, the descending and ascending communication from the brain to the peripheral sensors and vice versa are abruptly altered. Because of the primary trauma and the consequent secondary damage and loss of innervation, a cascade of degenerating and adaptive responses is activated. The main goal of this Special Issue is to focus on collecting new advances describing the molecular and cellular mechanisms involved in the SCI pathological process, as well as adaptative spontaneous responses and therapeutical approaches. Novel transcriptional regulations, funtional neuronal, glial, or other infiltrated cell entity responses, or therapeutical molecular or cellular experimental approaches will highly contribute to better defining the molecular and cellular scenario of the injured spinal cord and the consequent structural and funtional adaptive process.
Dr. Victoria Moreno-Manzano
Guest Editor
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Keywords
- spinal cord injury
- molecular changes
- neuronal degeneration
- circuit regeneration
- transcriptomics
- cell imaging
- single-cell analysis
- cell communication
- behavior
- functional outputs
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