Unveiling Mental Disorders: Molecular Mechanisms and Innovative Therapies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 25 July 2025 | Viewed by 543
Special Issue Editor
Interests: neurobiology; mental health; molecular and cellular biolog; intergenerational trauma; Indigenous mental health; psychedelic research; psychiatric disorders
Special Issue Information
Dear Colleagues,
This Special Issue aims to explore cutting-edge research on the molecular underpinnings of mental health disorders and novel therapeutic approaches. Advances in genetics, epigenetics, and neurobiology have transformed our understanding of psychiatric illnesses, revealing the intricate roles of genes, epigenetic modifications, and disrupted neural circuits in conditions such as depression, schizophrenia, and anxiety disorders.
We welcome submissions investigating molecular mechanisms, including gene expression changes, epigenetic alterations, neurotransmitter system dysregulation, and neuroplasticity deficits. Of particular interest are studies examining the interplay between genetic susceptibility and environmental factors in mental illness onset and progression.
In addition, we encourage the submission of papers presenting novel treatment approaches targeting recently identified molecular pathways. This includes pharmacological approaches like rapid-acting antidepressants, as well as emerging therapies such as psychedelics, neuromodulation techniques, and personalized medicine informed by genetic profiles.
Additionally, we seek the submission of research on the role of inflammation, oxidative stress, and mitochondrial dysfunction in mental illness. Investigations into the gut–brain axis, circadian rhythm disruptions, and the impact of diet on mental health and diseases are also of interest. We welcome studies utilizing innovative approaches such as neuroimaging, proteomics, and single-cell sequencing to elucidate disease mechanisms.
By bringing together diverse perspectives on molecular mechanisms and novel interventions, this Special Issue aims to advance our understanding of mental health disorders and accelerate the development of effective therapies.
Dr. Blerida Banushi
Guest Editor
Manuscript Submission Information
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Keywords
- molecular psychiatry
- epigenetics
- neurobiology
- gene–environment interactions
- neuroplasticity
- psychopharmacology
- neuromodulation
- personalized medicine
- neuroinflammation
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