New Aspects of Steroid Hormone Action in Hormone Dependent Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 3428
Special Issue Editor
Interests: estrogens; androgens; progestagens; steroid transporters; steroid biosynthetic and metabolic enzymes; hormone-dependent diseases; intracrine action; inhibitors; biomarkers
Special Issue Information
Dear Colleagues,
Steroid hormones have a plethora of roles in human health and disease, and the number of newly identified functions in the human body continues to expand. Classical and non-classical roles of steroid hormones can be explained by endocrine, paracrine, autocrine and intracrine actions, and intracellularly by genomic and non-genomic signalling. Alterations in biosynthesis and the actions of steroid hormones are implicated in the development of various hormone-dependent diseases, including hormone-dependent cancers and several benign pathologies. Despite the years of research, there remains a significant lack of knowledge, especially about androgens in female diseases and oestrogens in diseases that affect males. The involvement of other steroid hormones and their metabolites in disease has also not been delineated in detail yet. This Special Issue will cover different aspects of steroid hormone actions in hormone-dependent diseases, with particular emphasis on steroid profiling in tissues and physiological fluids, biosynthesis and metabolism studies, and the molecular mechanisms that underlie the intracrine actions of steroid hormones. This Special Issue thus aims to contribute to the rapidly expanding knowledge regarding the involvement of steroid hormones in the pathophysiology of human diseases.
Dr. Tea Lanišnik Rižner
Guest Editor
Manuscript Submission Information
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Keywords
- androgens
- estrogens
- progestagens
- hormone-dependent diseases
- biomarkers
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