Molecular Researches in Neuroinflammation and Brain Tumors
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (15 July 2023) | Viewed by 7257
Special Issue Editor
Interests: cancer; cancer biomarkers; cancer biology; apoptosis; cell signaling; cell proliferation; molecular cell biology; cancer cell biology
Special Issue Information
Dear Colleagues,
Many complex diseases, such as brain tumors, pose a challenge to identify the most effective therapeutic interventions, because current therapies often target specific aspects of the disorders. Due to the multiple causes of such diseases and the heterogeneity of patients, approaches focused on single targets present limited efficacy, overlooking important aspects of disease pathophysiology. A promising therapeutic approach to meet this challenge is to combine different therapies, while increasing therapeutic efficacy.
The aim of this Special Issue is to highlight novel targeted biomarkers involved in pathophysiology of these complex diseases and further develop combinatorial therapies tailored to the needs of individuals or stratified patient groups.
The combination of conventional therapies with molecular therapies emerged from the necessity of manipulating several antitumor processes. Results from multiple studies addressing tumor resistance to targeted therapies have shown that tumors must be attacked on several fronts, enabling the development of personalized/precision medicine.
We warmly welcome submissions, including original papers and reviews. Our Special Issue will focus on, but is not restricted to:
- Tumor profiling for the discovery of novel targeted biomarkers;
- The role of inflammation in brain pathologies, including, but not limited to, brain tumors;
- Synergistic combination treatment targeting signaling networks;
- Targeting the cross-talk between cancer stem cells, cancer cells, and the tumor microenvironment;
- Immunotherapy combinations in brain tumors;
- Mechanisms of resistance in combined immunotherapies;
- Adoptive cellular therapy in these complex diseases;
- Therapeutic modulation of the gut–brain axis in brain pathologies;
- Natural products—an emerging therapeutic approach in combinatorial therapy;
- Combination strategies for precision medicine.
Prof. Dr. Cristiana Tanase
Guest Editor
Manuscript Submission Information
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Keywords
- brain tumor
- neuroinflammation
- combinatorial therapies
- novel targeted biomarkers
- tumor microenvironment
- immunotherapy
- gut–brain axis
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