ijms-logo

Journal Browser

Journal Browser

G Protein-Mediated Signalling in Plants

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Plant Sciences".

Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 10700

Special Issue Editor


E-Mail Website
Guest Editor
Indian Institute of Science Education and Research (IISER), Tirupati, India
Interests: Plants; G Proteins; Growth and Development; Hormones; Molecular Communication; Receptor; Root Nodule; Signal Transduction; Symbiosis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues, 

Heterotrimeric G-proteins function as molecular switches during signaling to regulate diverse physiological functions in eukaryotes. Predominantly, G proteins, comprising of α-, β-and γ-subunits, transduce a wide variety of extracellular stimuli to generate a plethora of cellular responses.  In a the resting state, GDP-bound α-subunit is complexed with the β- and γ-subunits. The exchange of GDP bound on the α-subunit with GTP leads to the dissociation of α subunit from βγ dimer resulting in two functional subunits (α and βγ), which modulate various cellular pathways by binding with effectors. The G-protein deactivation occurs, when G-proteins hydrolyze GTP by the action of GAPs, like RGS, thereby accelerating the termination of signaling. In animals, the regulatory cycle of G-proteins depends on activation/inactivation through GPCR; whereas in plants the conventional G-protein regulation by GPCR is still questionable. With the advancements of biological and computational techniques, myriad progress has been made in understanding the mechanisms by which G-proteins turn on or off by signal-receptor interactions as well as regulate their downstream targets in plants. 

This Special Issue of IJMS will provide a comprehensive overview of this exciting and emerging field of G-proteins for a better understanding of their critical role in mediating signal transduction in plant cells. The current Special Issue is open to submission of previously unpublished experimental, theoretical, prospective, and review papers. 

Dr. Swarup Roy Choudhury
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Biotic and abiotic stress
  • Cell signaling
  • Effectors
  • Endocytosis
  • GTPase-accelerating proteins
  • Growth and Development
  • Heterotrimeric G proteins
  • Hormone
  • Interaction network
  • Phosphorylation
  • Receptor-like kinases

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Review

14 pages, 1339 KiB  
Review
Heterotrimeric G Proteins in Plants: Canonical and Atypical Gα Subunits
by Natsumi Maruta, Yuri Trusov, Alan M. Jones and Jose R. Botella
Int. J. Mol. Sci. 2021, 22(21), 11841; https://doi.org/10.3390/ijms222111841 - 31 Oct 2021
Cited by 14 | Viewed by 5608
Abstract
Heterotrimeric GTP-binding proteins (G proteins), consisting of Gα, Gβ and Gγ subunits, transduce signals from a diverse range of extracellular stimuli, resulting in the regulation of numerous cellular and physiological functions in Eukaryotes. According to the classic G protein paradigm established in animal [...] Read more.
Heterotrimeric GTP-binding proteins (G proteins), consisting of Gα, Gβ and Gγ subunits, transduce signals from a diverse range of extracellular stimuli, resulting in the regulation of numerous cellular and physiological functions in Eukaryotes. According to the classic G protein paradigm established in animal models, the bound guanine nucleotide on a Gα subunit, either guanosine diphosphate (GDP) or guanosine triphosphate (GTP) determines the inactive or active mode, respectively. In plants, there are two types of Gα subunits: canonical Gα subunits structurally similar to their animal counterparts and unconventional extra-large Gα subunits (XLGs) containing a C-terminal domain homologous to the canonical Gα along with an extended N-terminal domain. Both Gα and XLG subunits interact with Gβγ dimers and regulator of G protein signalling (RGS) protein. Plant G proteins are implicated directly or indirectly in developmental processes, stress responses, and innate immunity. It is established that despite the substantial overall similarity between plant and animal Gα subunits, they convey signalling differently including the mechanism by which they are activated. This review emphasizes the unique characteristics of plant Gα subunits and speculates on their unique signalling mechanisms. Full article
(This article belongs to the Special Issue G Protein-Mediated Signalling in Plants)
Show Figures

Figure 1

16 pages, 8035 KiB  
Review
Research Advances in Heterotrimeric G-Protein α Subunits and Uncanonical G-Protein Coupled Receptors in Plants
by Ying Liu, Xiaoyun Wang, Danhui Dong, Luqin Guo, Xiaonan Dong, Jing Leng, Bing Zhao, Yang-Dong Guo and Na Zhang
Int. J. Mol. Sci. 2021, 22(16), 8678; https://doi.org/10.3390/ijms22168678 - 12 Aug 2021
Cited by 7 | Viewed by 4007
Abstract
As crucial signal transducers, G-proteins and G-protein-coupled receptors (GPCRs) have attracted increasing attention in the field of signal transduction. Research on G-proteins and GPCRs has mainly focused on animals, while research on plants is relatively rare. The mode of action of G-proteins is [...] Read more.
As crucial signal transducers, G-proteins and G-protein-coupled receptors (GPCRs) have attracted increasing attention in the field of signal transduction. Research on G-proteins and GPCRs has mainly focused on animals, while research on plants is relatively rare. The mode of action of G-proteins is quite different from that in animals. The G-protein α (Gα) subunit is the most essential member of the G-protein signal cycle in animals and plants. The G-protein is activated when Gα releases GDP and binds to GTP, and the relationships with the GPCR and the downstream signal are also achieved by Gα coupling. It is important to study the role of Gα in the signaling pathway to explore the regulatory mechanism of G-proteins. The existence of a self-activated Gα in plants makes it unnecessary for the canonical GPCR to activate the G-protein by exchanging GDP with GTP. However, putative GPCRs have been found and proven to play important roles in G-protein signal transduction. The unique mode of action of G-proteins and the function of putative GPCRs in plants suggest that the same definition used in animal research cannot be used to study uncanonical GPCRs in plants. This review focuses on the different functions of the Gα and the mode of action between plants and animals as well as the functions of the uncanonical GPCR. This review employs a new perspective to define uncanonical GPCRs in plants and emphasizes the role of uncanonical GPCRs and Gα subunits in plant stress resistance and agricultural production. Full article
(This article belongs to the Special Issue G Protein-Mediated Signalling in Plants)
Show Figures

Figure 1

Back to TopTop