Nitric Oxide Synthases: Regulation and Function 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (20 April 2020) | Viewed by 4507
Special Issue Editor
Interests: cell culture; cholesterol metabolism; atherosclerosis; reactive oxygen species; signaling; endothelial cell biology; endothelial dysfunction; angiogenesis; vascular biology; vascular diseases; macrophage-foam cells; cardiovascular physiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Nitric oxide (NO) is a bioactive gas in the body and plays a crucial role in maintaining the homeostasis of the cardiovascular system. It can be synthesized by endothelial nitric oxide synthase (eNOS), neuronal NO synthase (nNOS), and inducible NO synthase (iNOS), which convert arginine into citrulline and produce NO in several cell types. In addition to its key role in regulating the cardiovascular function, NO has been reported to be involved in the pathological processes of a variety of human diseases, including cardiovascular diseases, metabolic diseases, inflammatory diseases, cancer, and neurological diseases. Given the importance of NOSs in the pathophysiology of human diseases, these enzymes are considered potential therapeutic targets for the treatment of diverse human pathologies. The Special Issue entitled "Nitric Oxide Synthases: Regulation and Function" aims to provide a research platform for the collection of the latest review and original research articles covering all aspects of these enzymes.
Prof. Dr. Tzong-Shyuan Lee
Guest Editor
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Keywords
- NOSs
- nitric oxide synthases
- isoforms
- nitric oxide
- endothelial cell
- stem cell
- cellular signaling
- redox pathway
- endothelial NOS
- neuronal NOS
- disease
- cancer
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