Remodeling of Mitochondria in Cancer and Other Diseases 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (15 January 2023) | Viewed by 4229
Special Issue Editor
Interests: metastasis; molecular pathway; cancer models; metabolism; tumor microenvironment; drug screening and development
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mitochondria are highly dynamic and responsive organelles that are capable of undergoing fission and fusion and are the hub for diverse signal processors, which are fundamental to cellular homeostasis, energy production, metabolism, survival, and death. Mitochondiral remodeling, including rearranging, recycling, and reprogramming, is essential for mitochondrial quality control, structural integrity, and functional interaction with other cellular organelles. Alhtough we are still far from fully understanding the complexity of mitochondrial remodeling in its physiological and pathophysiological significance, this process has been, nonetheless, implicated in the pathogenesis of many human disorders, including cancer and aging-related diseases. With the advent of new information, technologies, and methodologies, it is time to delineate the significance and enigmatic mechanisms relevant to the dynamic remodeling of mitochondria in response to pathophysiological stresses in a more precise and comprehensive way. In this respect, scientific evidence and provocative ideas are important to translate science into practice effectively. Therefore, we kindly invite you to contribute to this Special Issue with original research articles or comprehensive reviews on all molecular aspects related to the theme of “Remodeling of Mitochondria in Cancer and Other Diseases”. Short perspective papers or pure clinical papers will not be considered, while novel Communication articles with interesting molecular data will be of interest. This Special Issue aims to increase our understanding of the role, regulation, and impact of mitochondrial remodeling in disease-specific pathology and possibly translate these finding into therapeutics, from basic research to the clinic.
Dr. Yong Teng
Guest Editor
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Keywords
- mitochondrial biology
- mitochondrial remodeling
- mitochondrial biogenesis and bioenergetics
- mitochondrial dynamic network
- cancer development and progression
- mitochodria-associated human diseases
- mitochondria communication
- targeting mitochondria
- mitochondrial oncolgoy
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