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Oral and Maxillofacial Surgery: Current Updates and Perspectives
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Oral and Maxillofacial Surgery: Current Updates and Perspectives

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 4572

Special Issue Editor

Dr. Alessandro Antonelli

E-Mail Website
Guest Editor
Department of Health Sciences, School of Dentistry, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy
Interests: oral surgery; implant dentistry; oral rehabilitation; oral and maxillofacial surgery; regenerative dentistry; oral medicine
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, the field of oral and maxillofacial surgery (OMFS) has witnessed remarkable advancements, revolutionizing both medical and dental practices. This discipline encompasses the comprehensive diagnosis and treatment of conditions affecting the structures of the oral and maxillofacial regions, addressing both functional restoration and aesthetic enhancement.

From innovative diagnostic approaches to pioneering therapeutic methods, clinicians and researchers have improved the quality of life of patients. Moreover, the collaborative efforts between oral surgery, maxillofacial surgery and oral medicine have assumed paramount importance in optimizing patient care to solve the problems of oro-maxillary district. In this direction, research has focused on new therapeutic and diagnostic approaches in the management of oral diseases, on minimally invasive and more predictable surgical techniques for the rehabilitation of atrophic jaws, on the use of pre-surgical analytical methods based on 3D simulations, and the use of new approaches for hard and soft tissue regeneration. Consequently, the pursuit of excellence in therapeutic–diagnostic approaches demands unwavering dedication from both researchers and healthcare professionals.

In light of these remarkable developments, the focus of this new Special Issue is to continue the work carried out in the previous "Breakthroughs in Oral and Maxillofacial Surgery" and encourage and stimulate contributions from qualified and esteemed colleagues across the globe. Submissions are encouraged across a diverse spectrum of research domains, including, but not limited to the following:

  • Innovative therapeutic approaches in oral and maxillofacial surgery;
  • Three-dimensional implementations in diagnostic and pre-surgical analysis of oro-maxillary problems;
  • Innovations in the diagnosis and treatment of medication-related osteonecrosis of the jaws;
  • Mini-invasiveness in oral surgery treatments;
  • Advances in dental implantology;
  • New insights in oral potentially malignant disorders and oral cancer;
  • Management of oral disease.

We look forward to receiving your groundbreaking research contributions, as we collectively propelling the field of oral and maxillofacial surgery toward new frontiers of excellence.

Dr. Alessandro Antonelli
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • current updates in oral and maxillofacial surgery
  • new insights in oral medicine
  • advances in dental implantology
  • 3D pre-surgical evaluation in oral and maxillofacial surgery
  • regenerative dentistry

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Related Special Issue

Published Papers (4 papers)

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Research

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11 pages, 1666 KiB  
Article
Imaging Retrospective Study Regarding the Variability of the Osseous Landmarks for IAN Block
by Andrei Urîtu, Ciprian Roi, Alexandra Roi, Alexandru Cătălin Motofelea, Ioana Badea, Doina Chioran and Mircea Riviș
J. Clin. Med. 2025, 14(2), 636; https://doi.org/10.3390/jcm14020636 - 19 Jan 2025
Viewed by 524
Abstract
Background/Objectives: The aim of this study is to identify the most accurate and consistent landmarks for determining the precise location of the mandibular foramen (MF) and the mandibular ramus, suggesting appropriate adjustments to anesthesia techniques based on these variations in order to [...] Read more.
Background/Objectives: The aim of this study is to identify the most accurate and consistent landmarks for determining the precise location of the mandibular foramen (MF) and the mandibular ramus, suggesting appropriate adjustments to anesthesia techniques based on these variations in order to improve the success rate of the inferior alveolar nerve (IAN) block. Methods: CT scans of the mandibles from 100 patients were analyzed to measure the distance between the MF and various landmarks, including the sigmoid notch, gonion, posterior and anterior margins of the ramus, temporal crest, and the mandibular ramus height from the condyle to the gonion. The width of the mandibular ramus was also assessed, with correlations made to age and gender. Results: The MF was found to be closer to the sigmoid notch (mean = 21.2 mm), p = 0.393, than to the gonion (mean = 22.6 mm), p = 0.801, and closer to the posterior margin of the ramus (mean = 13.1 mm), p = 0.753, than to the anterior margin of the ramus. Additionally, the MF was closer to the temporal crest. Age also influenced the position of the MF, with a posterior and superior movement of the foramen, reducing the distance between the MF and the posterior margin of the ramus as well as the MF and the sigmoid notch (p < 0.001). Conclusions: A precise understanding of the MF’s location will help dentists and oral and maxillofacial surgeons improve the success of the IAN block, avoid injury to the inferior alveola neurovascular bundle, and minimize surgical complications such as paresthesia, permanent anesthesia, and hemorrhage. Full article
(This article belongs to the Special Issue Oral and Maxillofacial Surgery: Current Updates and Perspectives)
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10 pages, 619 KiB  
Article
The Prevalence and Diagnostic Patterns of Oral and Maxillofacial Lesions: A Seven-Year, Retrospective, Single-Center Cone Beam Computed Tomography and Histopathology Study in Saudi Arabia
by Shadi Alzahrani, Tagreed Wazzan, Abdulaziz Almaghrabi, Abdulaziz Alkhudran, Hamzah Aljereb, Shadia Elsayed and Albraa B. Alolayan
J. Clin. Med. 2024, 13(24), 7774; https://doi.org/10.3390/jcm13247774 - 19 Dec 2024
Viewed by 576
Abstract
Objective: To determine the prevalence of oral and maxillofacial lesions among patients at King Abdulaziz University from January 2016 to December 2022. Methods: This cross-sectional observational study included patients diagnosed with oral and maxillofacial intra-bony lesions based on radiological findings and confirmed [...] Read more.
Objective: To determine the prevalence of oral and maxillofacial lesions among patients at King Abdulaziz University from January 2016 to December 2022. Methods: This cross-sectional observational study included patients diagnosed with oral and maxillofacial intra-bony lesions based on radiological findings and confirmed by histopathological examination. The lesions were classified according to the fourth edition of the World Health Organization Classification of Head and Neck Tumors. Results: This study included 237 patients with a mean age of 31.53 ± 14.97 years, of which 45.1% were female. Most patients (46.7%) had mandibular lesions, followed by maxillary lesions (35.9%). Only 2.95% of the tumors were malignant. Odontogenic cysts were the most prevalent (65.40%), with radicular cysts and keratocytes being the most common types. The most prevalent tumor types were odontoma and ameloblastoma. The most malignant lesion was multiple myeloma. Conclusions: Our findings reveal that mandibular cystic lesions predominated, and emphasize the low incidence of malignancy in the study population. They provide valuable insights into the oral and maxillofacial lesion landscape at a high-volume tertiary care center. Full article
(This article belongs to the Special Issue Oral and Maxillofacial Surgery: Current Updates and Perspectives)
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20 pages, 3215 KiB  
Article
Epidemiologic Trends in Maxillofacial Trauma Surgery in Germany—Insights from the National DRG Database 2005–2022
by Axel Meisgeier, Simon Pienkohs, Florian Dürrschnabel, Laura Moosdorf and Andreas Neff
J. Clin. Med. 2024, 13(15), 4438; https://doi.org/10.3390/jcm13154438 - 29 Jul 2024
Cited by 1 | Viewed by 1024
Abstract
Background: Maxillofacial trauma (MFT) caused by falls, interpersonal violence or traffic accidents leading to fractures of different facial regions, including the midface and the mandible, are common clinical conditions requiring open reduction and internal fixation. The aim of this study was to analyze [...] Read more.
Background: Maxillofacial trauma (MFT) caused by falls, interpersonal violence or traffic accidents leading to fractures of different facial regions, including the midface and the mandible, are common clinical conditions requiring open reduction and internal fixation. The aim of this study was to analyze the incidence and time trends in MFT-associated surgeries regarding different facial regions in the German healthcare system over time. Materials and methods: Nationwide data regarding the national diagnosis-related group (DRG) inpatient billing system was received from the German Federal Statistical Office for the years 2005–2022. We estimated the age–gender standardized incidence of MFT-associated procedures classified by the Operation and Procedure Classification System (OPS) and evaluated age- and gender-adjusted time trends using Poisson regression analysis. Results: The total standardized incidence rate of MFT-associated procedures in the observational period 2005–2022 was 25.1 (♀13.3; ♂37.5) per 100,000 person-years within a slight significant annual decrease of 0.5%. A significant increase in the incidence of MFT-related procedures within the observational period was found in older adults from 60 to 79 years (+55.1%; ♀+54.8%; ♂+56.3%) and elderly patients over 80 years (+66.7%; ♀+59.1%; ♂+85.1%). Other significant trends are decreases in MFT-related procedures performed in children from 0–14 years (−28.1%; ♀−30.3%; ♂−27.3%) and young adults between 15 and 35 years (−20.4%; ♀−7.3%; ♂−22.5%). Conclusions: MFT-associated surgery is a persisting challenge in the German healthcare system. There is an ongoing transition in MFT-associated surgeries from younger to older patients beyond the scope of demographic change, highlighting the increasing importance of interdisciplinary treatment of patients with pre-existing conditions in maxillofacial surgery. Implementation of injury prevention measures might be beneficial in this population. Full article
(This article belongs to the Special Issue Oral and Maxillofacial Surgery: Current Updates and Perspectives)
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Review

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21 pages, 506 KiB  
Review
The Effect of Conservative vs. Radical Treatment of Ameloblastoma on Recurrence Rate and Quality of Life: An Umbrella Review
by Roberta Gasparro, Francesco Giordano, Maria Domenica Campana, Angelo Aliberti, Elena Landolfo, Pasquale Dolce, Gilberto Sammartino and Alessandro E. di Lauro
J. Clin. Med. 2024, 13(17), 5339; https://doi.org/10.3390/jcm13175339 - 9 Sep 2024
Cited by 1 | Viewed by 1929
Abstract
Ameloblastoma is a rare, benign, but locally aggressive odontogenic tumor that originates from the epithelial cells involved in tooth development. The surgical approach to treating an ameloblastoma depends on the type, size, location, and extent of the tumor, as well as the patient’s [...] Read more.
Ameloblastoma is a rare, benign, but locally aggressive odontogenic tumor that originates from the epithelial cells involved in tooth development. The surgical approach to treating an ameloblastoma depends on the type, size, location, and extent of the tumor, as well as the patient’s age and overall health. This umbrella review’s aim is to summarize the findings from systematic reviews (SRs) and meta-analyses on the effect of radical or conservative treatment of ameloblastoma on the recurrence rate and quality of life, to evaluate the methodological quality of the included SRs and discuss the clinical management. Three electronic databases (PubMed, Scopus, The Cochrane Library) were checked. The primary outcome was the recurrence rate after surgical treatment, while the secondary outcomes were the post-operative complications, quality of life, esthetic, and functional impairment. The methodological quality of the included SRs was assessed using the updated version of “A Measurement Tool to Assess Systematic Review” (AMSTAR-2). Eighteen SRs were included. The quality of the included reviews ranged from critically low (three studies) to high (eight studies). Four studies were included in meta-analysis, and they revealed that the recurrence rate is about three-times more likely in the conservative treatment group compared to the radical treatment group, and this result is statistically significant. Despite the high recurrence rate, the latter was more appropriate in the case of smaller lesions and younger patients, due to better post-operative quality of life and reduced functional and esthetic impairments. Based on the results of this overview, conservative treatment may be recommended as the first-line approach for intraosseous ameloblastoma not involving soft tissue. However, given the expectation of a higher recurrence rate, it is advisable to reduce the interval between follow-up visits. However, further prospective studies are needed to establish the best treatment choice and follow-up period. Full article
(This article belongs to the Special Issue Oral and Maxillofacial Surgery: Current Updates and Perspectives)
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