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Postoperative Pulmonary Complications and Care

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Emergency Medicine".

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 3862

Special Issue Editor


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Guest Editor
Director of Department of Anesthesiology, Intensive Care and Emergency Medicine, Pain Therapy, Bergmannstrost Hospital Halle, Halle, Germany
Interests: pulmonary physiology; acute respiratory distress syndrome; mechanical ventilation; ventilation during anesthesia; ventilation-induced lung injury; lung imaging; sepsis; antibiotic therapy; microdialysis; obesity
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Special Issue Information

Dear Colleagues,

More than 230 million surgical procedures are undertaken worldwide each year and postoperative complications after surgery are an important cause of death. General anesthesia usually requires mechanical ventilation, which imposes mechanical stress to the lungs and may have injurious effects to lung endo- and epithelium, and may aggravate pulmonary and systemic inflammatory responses to surgery. Postoperative pulmonary complications (PPC) have a strong impact on morbidity and mortality of surgical patients and mechanical ventilation strategy may influence the occurrence of PPCs. In recent years, experimental and clinical research has addressed the issue of pathogenesis of PPC and its prevention in the perioperative setting. This is especially true for certain groups of patients such as morbidly obese patients, patients undergoing large abdominal procedures, require single lung ventilation or cardiac surgery.

This special issue welcomes all experimental and clinical manuscripts which aim to extend our knowledge of pathophysiology and care of PPCs.

Prof. Dr. Hermann Wrigge
Guest Editor

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Keywords

  • mechanical ventilation
  • ventilation-induced lung injury
  • pneumonia
  • atelectasis
  • positive end-expiratory pressure
  • one lung ventilation
  • driving pressure
  • end-expiratory lung volume
  • respiration
  • anesthesia

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Published Papers (1 paper)

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Research

12 pages, 412 KiB  
Article
Effects of Sugammadex on Post-Operative Pulmonary Complications in Laparoscopic Gastrectomy: A Retrospective Cohort Study
by Jiwon Han, Jung-Hee Ryu, Bon-Wook Koo, Sun Woo Nam, Sang-Il Cho and Ah-Young Oh
J. Clin. Med. 2020, 9(4), 1232; https://doi.org/10.3390/jcm9041232 - 24 Apr 2020
Cited by 12 | Viewed by 3296
Abstract
The use of sugammadex can reduce post-operative residual neuromuscular blockade, which is known to increase the risk of post-operative respiratory events. However, its effect on post-operative pulmonary complications is not obvious. This study was performed to evaluate the effects of sugammadex on post-operative [...] Read more.
The use of sugammadex can reduce post-operative residual neuromuscular blockade, which is known to increase the risk of post-operative respiratory events. However, its effect on post-operative pulmonary complications is not obvious. This study was performed to evaluate the effects of sugammadex on post-operative pulmonary complications in patients undergoing laparoscopic gastrectomy between 2013 and 2017. We performed propensity score matching to correct for selection bias. Post-operative pulmonary complications (i.e., pneumonia, respiratory failure, pleural effusion, atelectasis, pneumothorax, and aspiration pneumonitis) were evaluated from the radiological and laboratory findings. We also evaluated admission to the intensive care unit after surgery, re-admission or an emergency room visit within 30 days after discharge, length of hospital stay, re-operation, and mortality within 90 days post-operatively as secondary outcomes. In the initial cohort of 3802 patients, 541 patients were excluded, and 1232 patients were analyzed after propensity score matching. In the matched cohort, pleural effusion was significantly reduced in the sugammadex group compared to the neostigmine group (neostigmine 23.4% vs. sugammadex 18%, p = 0.02). Other pulmonary complications and secondary outcomes were not significantly different between the groups. In comparison to neostigmine, the use of sugammadex was associated with a lower incidence of post-operative pleural effusion in laparoscopic gastrectomy. Full article
(This article belongs to the Special Issue Postoperative Pulmonary Complications and Care)
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