Mechanisms of Diseases
A section of Journal of Personalized Medicine (ISSN 2075-4426).
Section Information
Aim
The “Mechanisms of Diseases” section of the Journal of Precision Medicine aims to disseminate leading-edge scholarship on individual or personalized biomolecular mechanisms related to disease, disease progression, persistent disease remission, mechanisms of resistance, mechanisms of outstanding response, and mechanisms of regular response to therapy. We emphasize translational research, requiring validation using human cohorts, human tissues, or human-derived data, either retrospectively, prospectively, or through meta-analyses. We encourage submissions that explore complex biomolecular interactions and patterns, including those spanning different biological scales, exploring synergistic and antagonistic effects of distinct biomolecular mechanisms that may interact in an individual manner and confer paradoxical resistance of or risk factors not more otherwise explained by simple additive and subtractive effects of risks. We strongly encourage the submission of articles that focus on predictive analytics and biomarkers, including those that involve multiple variables (e.g., multi-omics, biomolecular pathways, clinical imaging, clinical data, or a combination of these ) rooted in causal biomolecular mechanisms. Download Section Flyer
Scope
- Individualised Biomolecular Mechanisms of Disease/Insights into the underlying biomolecular mechanisms contributing to the development of specific diseases.
- Individual Disease Progression/Investigation into the biomolecular mechanisms that drive the progression of diseases.
- Persistent Individual Disease Remission/Explore the mechanisms responsible for maintaining disease remission over extended periods.
- Mechanisms of Individual Resistance to Therapy/Address the biomolecular mechanisms that underlie resistance to therapies or interventions.
- Mechanisms of Exceptional Individual Response to Therapy/Elucidate the biomolecular mechanisms that lead to exceptional responses to treatments.
- Mechanisms Explaining Individualized Probability of Response to Therapy/Focus on the biomolecular mechanisms associated with typical responses to therapeutic interventions.
Editorial Board
Special Issues
Following special issues within this section are currently open for submissions:
- Chronic Liver Disease: New Targets and New Mechanisms (Deadline: 20 February 2025)
- The Challenges and Therapeutic Prospects in Cardiovascular Disease (Deadline: 20 February 2025)
- Diagnosis, Management, and Future Opportunities in Multiple Sclerosis (Deadline: 28 February 2025)
- Pathogenesis and Personalized Treatment of Respiratory Diseases (Deadline: 10 March 2025)
- Pathology and Molecular Diagnostics in the Personalized Treatment of Lung Diseases (Deadline: 20 March 2025)
- Cardiology and Cardio-Oncology: Pathogenesis, Diagnosis and Treatment (Deadline: 20 March 2025)
- Oxidative Stress and Antioxidant Therapy in Diseases (Deadline: 30 March 2025)
- Dermatology: Diagnosis and Personalized Treatment (Deadline: 15 April 2025)
- Targeted Therapy and Biomarkers for Solid Tumors (Deadline: 20 April 2025)
- Novel Challenges and Advances in Pediatric Hematology and Hematologic Malignancies (Deadline: 25 April 2025)
- Diabetes Mellitus: Current Research and Future Perspectives, 2nd Edition (Deadline: 20 May 2025)
- Novel Therapeutic Approaches in Oral and Maxillofacial Surgery (Deadline: 25 May 2025)
- Brain Tumor Microenvironment and Host Role: Implications for Immunotherapy (Deadline: 25 May 2025)
- Towards Precision Medicine in Parkinson’s Disease (Deadline: 25 June 2025)
- Respiratory Disease: Diagnosis, Treatment and Prognosis (Deadline: 30 June 2025)
- Endometriosis: Updates on the Etiology, Pathophysiology, Measurements and Therapeutics (Deadline: 15 July 2025)
- Retinal Diseases: Mechanisms, Diagnosis and Treatments (Deadline: 20 July 2025)
- New Advances in the Prevention and Treatment of Neurological Diseases (Deadline: 20 July 2025)
- Gynecologic Oncology: Molecular Mechanisms, Diagnostics and Therapy (Deadline: 25 July 2025)
- AI and Precision Medicine: Innovations and Applications (Deadline: 31 July 2025)
- Novel Challenges and Advances in Respiratory Diseases (Deadline: 31 July 2025)
- Personalized Prevention of Gallbladder Cancer (Deadline: 31 August 2025)
- Pathological Mechanism of Breast Cancer (Deadline: 25 September 2025)
- Personalized Medicine in Metabolism Disorders (Deadline: 10 October 2025)
- Gestational Diabetes: Challenges and Cutting-Edge Research (Deadline: 15 October 2025)
- Innovations in Airway Diseases (Deadline: 31 October 2025)
- Current Status and Future Prospects of Histopathology in Cancer Diagnosis (Deadline: 31 October 2025)
- Digital Pathology in Translational Medicine and Clinical Practice (Deadline: 31 December 2025)