Recent Insights in the Pathogenesis, Diagnosis, Prognosis and Treatment of Glomerular Disorders

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 29 April 2025 | Viewed by 131

Special Issue Editors


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Guest Editor
1. “Dr. C.I. Parhon” University Hospital, Iasi, Romania
2. Faculty of Medicine, “Grigore T. Popa” University of Medicine, Iasi, Romania
Interests: immunology; renal transplantation; glomerular diseases; cardiovascular disease; dialysis; pathology

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Guest Editor
“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Fundeni Clinical Institute, Bucharest, Romania
Interests: glomerular disorders; rare genetic kidney disorders; immunology; systemic autoimmune disorders with renal involvement; biomarkers; diabetic kidney disease
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Special Issue Information

Dear Colleagues,

Glomerular disorders are the third-leading cause of end-stage kidney disease worldwide. Significant progress has been made during the past decades in the understanding of the pathogenesis of glomerular disorders (e.g., IgA nephropathy, membranous nephropathy, lupus nephritis, ANCA-associated vasculitis, and C3 glomerulopathy), which has translated into better prognostication and development of targeted therapies with the potential to significantly alter the long-term patient and renal survival in such disorders. Nonetheless, despite these tremendous advances, the adequate diagnosis of the underlying glomerular disorders and the indications/availability of kidney biopsies still vary significantly across different regions of the world. Thus, there is still a need to better define the epidemiology of glomerular disorders across different regions and populations to further understand the contributing factors to glomerular disorders pathogenesis, evaluate the impact of genetic predisposition in these circumstances, better delineate the factors associated with treatment response and long-term renal survival, and refine treatment approaches in terms of minimizing the adverse effects of immunosuppressive therapy.

This Special Issue welcomes both original and review papers approaching the previously defined gaps in the knowledge of individual glomerular disorders. Nonetheless, studies evaluating glomerular disorders from kidney biopsy registries from individual clinics or geographic regions will also be considered, as there is an unmet need to better define the epidemiology and prognosis of these disorders in distinct parts of the world.

Prof. Dr. Adrian Constantin Covic
Prof. Dr. Gener Ismail
Guest Editors

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Keywords

  • glomerular disorders
  • pathology
  • kidney biopsy
  • immunology
  • immunosuppresion
  • vasculitis

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