Development and Application of Marine-Derived Anti-cancer Agents
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 15649
Special Issue Editor
Interests: marine natural products; anticancer; pigments; microalgae; chemosensitization
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Marine organisms are known to synthesize a diversity of molecules with unique structural skeletons and remarkable applications in the pharmaceutical, food, and cosmetic industries. Marine-derived bioactive compounds include polysaccharides, sterols, proteins, polyunsaturated fatty acids (PUFAs), pigments, etc. These compounds are capable of inhibiting cell growth and migration, inducing cell cycle arrest and apoptosis, and restoring the sensitivity of tumor cells to conventional anticancer drugs. In recent decades, the use of marine compounds in combination with classical cytotoxic agents has emerged as a new approach to circumvent tumor resistance mechanisms.
Despite their undeniable anticancer potential, limiting factors have hindered the clinical use of marine natural products, such as the development of ecofriendly scaled-up extraction and purification processes and the lack of solid preclinical data.
In this Special Issue, we invite you to publish reviews or original articles dealing with, but not limited to, the following topics:
- Extraction, isolation, and characterization;
- Metabolomic profile of marine-derived products;
- Scaled-up extraction and purification methods;
- Ecofriendly strategies to obtain anticancer compounds;
- Anticancer activity of extracts, enriched fractions, or isolated compounds;
- Innovative mechanisms of action;
- Marine natural products as chemosensitizing agents;
- Toxicological and pharmacokinetic investigations;
- Technological development of new marine-based formulations.
Dr. Raimundo Gonçalves de Oliveira Junior
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- anticancer molecules
- marine biotechnology
- tumor sensitization
- drug discovery
- ecofriendly extraction and purification
- secondary metabolites
- multidrug resistance
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