Nanoparticles for Biological Imaging and Treatment Applications
A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".
Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 3136
Special Issue Editor
The Malone Center for Engineering in Healthcare (https://malonecenter.jhu.edu)
Department of Electrical and Computer Engineering, Whiting School of Engineering; Department of Biomedical Engineering; School of Medicine Johns Hopkins University, Baltimore MD
Interests: theranostics; laser tissue interactions; multimodal imaging snd treatment; design of biomedical instruments and systems; practical ethics
Special Issue Information
Dear Colleagues,
The progress in nanotechnology, wave propagation in tissue, and understanding of disease biological markers enables new and powerful methods for early detection, treatment, and monitoring. It is now possible to fabricate different types and shapes of uniform nanoparticles: nanospheres, nanorods, and nanocages. They can also be biocompatible. These particles can be functionalized so they can specifically bind to disease markers. They can be adhered to surfaces such as fiber tips and band-aids. It is possible to manipulate them and drive them to certain areas within the body, and they can be used as a conversion mechanism from one energy type to another. Nanoparticles can be magnetic superparamagnetics. They can emit different wavelengths of light from the excitation wavelength. They can emit acoustical waves after being triggered with magnetic fields, and they can emit heat locally with magnetic or light excitation. Nanoparticles can be used for treatment by themselves or enhance chemotherapeutic agents’ effect on the disease. Nanocages can carry drugs and can release them in a controllable way in an area where they are needed. This can be done with outside energy or self-opening when in a certain conditions (i.e., pH). Various imaging modalities such as MRI, magnetic particle imaging, magnetoacoustics, thermal imaging, and other optical methods are adapted, further developed or totally new and used for nanoparticle imaging. Imaging can be done with big expensive machines or portable bedside instruments. Nanoparticles are excellent vehicles for development of theranostics applications.
This Special Issue has been created to report all these fascinating advances in medical applications. We are seeking high-level manuscripts that report the newest results in the field.
Prof. Israel Gannot
Guest Editors
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Keywords
- Early diagnostics of cancer
- Multimodal cancer imaging
- Nanoparticle-based hyperthermia
- Tumor-immune response
- Immunotherapy
- Nanoparticle functionalization
- Specific binding
- Enhanced chemotherapy
- Temperature
- Functional imaging
- Nanorods
- Nanocages
- Antibody–antigen reaction
- Tumor localization
- Nanoparticle manipulation
- Heat transfer in tissue around tumors
- Functional imaging of tumors
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