Advances in Calcium Phosphate Bone Cements
A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".
Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 3690
Special Issue Editor
2. Institute of Chemical Engineering Sciences (FORTH/ICE-HT), GR 26504 Patras, Greece
Interests: biomaterials; gels; calcium phosphates; biomineralization; alginates; zinc oxide; calcium oxalate
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Special Issue Information
Dear Colleagues,
Bone defects can be caused by tumors resection, injuries, or other pathologic situations. Managing of bone defects is important since they can cause serious disability problems. The use of biomaterials to heal bone defects targets both functional and aesthetic rehabilitation of the patient. Calcium phosphate bone cements (CPCs) have been used in clinical practice since the early nineties in managing bone defects. The in situ hardening and injectability of CPCs are one of the advantages in comparison to other reshaped synthetic grafts such as bioceramics. Calcium phosphate bone cements are prepared by mixing a solid and liquid phase. The solid phase consists of one or more salts containing phosphate and calcium and the liquid phase involves water or an aqueous phosphate solution. Mixing these two phases at room temperature produces a mixture that hardens over time due to the development of hydroxyapatite or brushite crystals. The cement is applied to the injured area, shaped by the surgeon, and, finally, it will decompose over time and replaced by the newly formed bone.
The articles presented in this Special Issue will cover various topics, ranging from materials preparation, the chemistry of cement hardening, textural and structural characterization, mechanisms of transformation into calcium deficient hydroxyapatite or brushite, modern methods of producing CPCs scaffolds such as 3D printing, and clinical applications of CPCs. It is our pleasure to invite you to submit review articles, original papers, and communications for this Special Issue "Advances in Calcium Phosphate Bone Cements".
Prof. Dr. Nikolaos Bouropoulos
Guest Editor
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Keywords
- Synthesis and characterizations of CPCs
- Mechanical properties of CPCs
- Composite CPCs
- 3D printing of CPCs
- CPPCs as drug delivery systems
- α-tricalcium phosphate transformation
- Theoretical and computational studies on CPCs
- Cement based calcium phosphate bone grafts
- Porous CPCs
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