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Additive Manufacturing of Bioceramics, Bioglasses and Calcium Phosphates

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (10 May 2022) | Viewed by 3274

Special Issue Editors


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Guest Editor
Department of Functional Materials in Medicine and Dentistry, Würzburg University, Würzburg, Germany
Interests: calcium phosphate cement chemistry; degradable magnesium phosphate cements; additive manufacturing approaches; cement-polymer composites
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Guest Editor
Centre for Translational Bone, Joint and Soft Tissue Research, Faculty of Medicine and University Hospital, Technische Universität Dresden, 01307 Dresden, Germany
Interests: biomaterials; calcium phosphates; biopolymers; 3D printing; tissue engineering
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Additive manufacturing (AM) methods such as selective laser sintering, 3D powder printing, stereolithography or extrusion-based dispense plotting are increasingly used for the fabrication of patient-specific bioceramic implants and scaffolds for bone tissue engineering. The methods allow a near net-shape production of micro- and macroporous ceramics from a wide variety of compositions ranging from bioinert zirconia or alumina to bioactive calcium phosphates and bioglasses. Each method provides specific advantages, e.g., a high spatial resolution for stereolithography, high initial strength resulting from laser sintering, and the ability to work at room temperature for powder printing and dispense plotting when cold setting cements are used. The latter offers the possibility to simultaneously process bioceramic and biopolymer inks to create composites with enhanced material and biological properties. In addition, sensitive drugs or growth factors can directly be included in the fabrication process.

The present Special Issue aims to provide an overview of the state of the art in additive manufacturing of bioceramics and bioglasses and respective composite materials for medical applications and give insights into novel research directions in this fast-developing field of research.

We invite all colleagues to submit manuscripts (full papers, communications, and reviews) to this Special Issue. Submitted manuscripts may cover all aspects, ranging from basic materials development of bioceramics and bioglasses for AM to novel fabrication approaches, post-processing regimes to adjust material and biological properties, and in vitro and in vivo testing of printed constructs.

Prof. Dr. Uwe Gbureck
Prof. Dr. Michael Gelinsky
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioceramics
  • bioglass
  • calcium phosphate
  • additive manufacturing
  • 3D printing
  • bone replacement
  • scaffolds

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Published Papers (1 paper)

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Research

14 pages, 2641 KiB  
Article
Extrusion-Based 3D Printing of Calcium Magnesium Phosphate Cement Pastes for Degradable Bone Implants
by Lisa-Marie Götz, Katharina Holeczek, Jürgen Groll, Tomasz Jüngst and Uwe Gbureck
Materials 2021, 14(18), 5197; https://doi.org/10.3390/ma14185197 - 10 Sep 2021
Cited by 14 | Viewed by 2755
Abstract
This study aimed to develop printable calcium magnesium phosphate pastes that harden by immersion in ammonium phosphate solution post-printing. Besides the main mineral compound, biocompatible ceramic, magnesium oxide and hydroxypropylmethylcellulose (HPMC) were the crucial components. Two pastes with different powder to liquid ratios [...] Read more.
This study aimed to develop printable calcium magnesium phosphate pastes that harden by immersion in ammonium phosphate solution post-printing. Besides the main mineral compound, biocompatible ceramic, magnesium oxide and hydroxypropylmethylcellulose (HPMC) were the crucial components. Two pastes with different powder to liquid ratios of 1.35 g/mL and 1.93 g/mL were characterized regarding their rheological properties. Here, ageing over the course of 24 h showed an increase in viscosity and extrusion force, which was attributed to structural changes in HPMC as well as the formation of magnesium hydroxide by hydration of MgO. The pastes enabled printing of porous scaffolds with good dimensional stability and enabled a setting reaction to struvite when immersed in ammonium phosphate solution. Mechanical performance under compression was approx. 8–20 MPa as a monolithic structure and 1.6–3.0 MPa for printed macroporous scaffolds, depending on parameters such as powder to liquid ratio, ageing time, strand thickness and distance. Full article
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