Advanced Technologies in Pediatric Nephrology

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Pediatrics".

Deadline for manuscript submissions: 20 January 2025 | Viewed by 730

Special Issue Editor


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Guest Editor
Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
Interests: kidney; nephrology; transplantation; hypertension; UTI; glomerulonephritis

Special Issue Information

Dear Colleagues,

In this Special Issue, we plan to provide a practical source of information about the common topics in a format that is clear to understand and accessible to all health care professionals involved in treating children and adolescents with kidney diseases. We believe that the open access nature of the journal fulfills this mission. We also aim to refine the knowledge base in pediatric nephrology, where significant advances have been made, and highlight improvements in clinical management. The study areas that we aim to cover are glomerular diseases, advances in management of pediatric hypertension, childhood nephrotic syndrome, advances in lupus nephritis, different aspects of chronic kidney disease, advances in different modalities of renal replacement therapy, advances in kidney transplantation, voiding dysfunction in children, renal tubular diseases, and genetics in renal diseases.

We will solicit original research articles, systematic reviews, meta-analyses, and reviews pertaining to these topics. 

Dr. Kiran K. Upadhyay
Guest Editor

Manuscript Submission Information

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Keywords

  • pediatrics
  • kidney transplantation
  • dialysis
  • hypertension
  • nephrotic syndrome
  • glomerulonephritis
  • lupus nephritis
  • chronic kidney disease
  • voiding dysfunction
  • renal tubular disease

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Published Papers (1 paper)

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8 pages, 1046 KiB  
Case Report
Association of Oral Tobacco-Free Nicotine Delivery Product with Acute Renal Tubular Necrosis
by Ratna Acharya, William Clapp and Kiran Upadhyay
Medicina 2024, 60(11), 1846; https://doi.org/10.3390/medicina60111846 - 9 Nov 2024
Viewed by 507
Abstract
Usage of novel non-tobacco oral nicotine delivery products (ONDPs) has been increasing among adolescents in the United States. It is presumed that they are less toxic than their tobacco-containing counterparts, but that has not been examined in controlled studies. Most of the studies [...] Read more.
Usage of novel non-tobacco oral nicotine delivery products (ONDPs) has been increasing among adolescents in the United States. It is presumed that they are less toxic than their tobacco-containing counterparts, but that has not been examined in controlled studies. Most of the studies have focused on non-renal manifestations of tobacco consumption via different means. The renal manifestations of non-tobacco ONDPs are not very well known, especially in immunocompromised patients. A 19-year-old male transplant recipient presented with flank pain and a few days’ history of intake of ZYNR pouches. Immunosuppression was with tacrolimus, mycophenolate, and steroids. Baseline serum creatinine was 1.1–1.3 mg/dL. Laboratory evaluation showed elevated C-reactive protein, increased serum creatinine and blood urea nitrogen, leukocytosis, neutrophilia, and increased lactate dehydrogenase (LDH). Infectious disease work-up was negative. A kidney transplant biopsy showed severe acute tubular injury/necrosis (ATN) without evidence of rejection. Donor-specific antibodies were negative. Other etiologies of hemolysis were negative. He did not require renal replacement therapy. Kidney function and LDH improved gradually. The most recent follow-up eight months after presentation showed a serum creatinine level of 2.6 mg/dL with stable electrolytes, with eGFR of 35 mL/min/1.73 m2. Here, we describe a 19-year-old adolescent with a kidney transplant who sustained ATN leading to advanced chronic disease apparently following the usage of non-tobacco ONDP. Further larger studies are needed to study ATN as a possible renal manifestation of these next-generation products to raise awareness among the public. Full article
(This article belongs to the Special Issue Advanced Technologies in Pediatric Nephrology)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Pediatric Nephrology
Authors: Carlos Araya
Affiliation: Nemours Childrens Health, Orlando, FL, USA

Title: Lupus nephritis
Authors: Nisha Mathews
Affiliation: Nemours Childrens Health, Orlando, FL, USA

Title: Different modalities of renal replacement therapy
Authors: Aura Arenas Morales
Affiliation: Nemours Childrens Health, Orlando, FL, USA,

Title: Pediatric Nephrology
Authors: Naile Tufan Pekkucuksen
Affiliation: Childrens Mercy Hospital, Kansas City, MO, USA

Title: Pediatric Urology
Authors: Cynthia Sharadin
Affiliation: University of Florida, Gainesville, FL, USA

Title: Pediatric Nephrology
Authors: Ahmad Aldughiem
Affiliation: Dayton Childrens Hospital, Dayton, OH, USA

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