Diagnosis and Treatment of Severe Asthma
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Pulmonology".
Deadline for manuscript submissions: 15 February 2025 | Viewed by 1739
Special Issue Editor
Special Issue Information
Dear Colleagues,
It is a pleasure to invite you to contribute to this Special Issue.
The ERS/ATS taskforce defines severe uncontrolled asthma (SUA) as, “asthma which requires treatment with high dose inhaled corticosteroids (ICS) plus a second controller (and/or systemic corticosteroids) to prevent it from becoming ‘uncontrolled’ or which remains uncontrolled despite this therapy”.
It is important to state that severe uncontrolled asthma shall be diagnosed only after considerable effort is made to address potential complicating factors, primarily medication adherence, as well as medication administration techniques, allergen exposure, smoking, and others. When this diagnostic criteria is applied, approximately 5% of patients with asthma fit the diagnosis of SUA. Considering the fact that asthma affects millions of patients in different countries, it is apparent that the burden of SUA is high. The obvious link between SUA in children and the development of COPD later in life makes it imperative that the SUA is managed appropriately and full controlled is achieved.
Given the extremely high interest in this topic from both researchers and medical practitioners, Medicina is launching a Special Issue entitled "Diagnosis and Treatment of Severe Asthma". The aim of this Special Issue is to explore the issues related to the pathogenesis of SUA, with special attention paid to its phenotypes and the role of complicating factors which affect its management.
We are pleased to invite submissions of original articles concerning basic and clinical research in severe asthma in children and adults, as well as interesting case reports, perspectives, reviews, systematic reviews, and meta-analyses focusing on topics including, but not limited to, the following:
- Phenotypes and endotypes of SUA, with special attention paid to airway sampling;
- Airway remodeling and its potential management;
- Eosinophilic and reflux esophagitis as an important example of comorbidity for SUA;
- Role of obesity in SUA;
- Strategies for choosing biological medications for SUA.
Prof. Dr. Mikhail Kazachkov
Guest Editor
Manuscript Submission Information
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Keywords
- severe asthma
- severe pediatric asthma
- asthma phenotypes
- asthma comorbidities
- esophagitis and asthma
- biological medications for asthma
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