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Medicina
Special Issues
Current Developments in Diagnostic and Therapeutic Aspects of Genitourinary Tumors
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Current Developments in Diagnostic and Therapeutic Aspects of Genitourinary Tumors

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Oncology".

Deadline for manuscript submissions: 15 January 2025 | Viewed by 370

Special Issue Editor

Dr. Lucio Dell'Atti

E-Mail Website
Guest Editor
Division of Urology, Unit of Quality and Risk Management, University Hospital of Marche, Ancona, Italy
Interests: robotic surgery; kidney cancer; prostate cancer; andrology

Special Issue Information

Dear Colleagues,

Genitourinary cancers occur in the urinary tract, bladder, and kidney and are also found in the male reproductive system, prostate, ureter, penis, and testicles. Of these, prostate and bladder cancers are within the top 10 most common cancers in men. Usually, due to cancers frequently being diagnosed at an advanced stage, treatment options are limited and a cure is not possible. Every day, expert, specialized surgeons, as well as medical and radiation oncologists, work in collaboration to plan the diagnosis and management of care when faced with patients with these problems. Improvements in diagnostic tools, partly based on artificial intelligence, and numerous promising biomarker candidates for various clinical purposes have helped promote increasingly minimally invasive and personalized treatments. This Special Issue of Medicina aims to discuss novel diagnostics and treatment strategies, sharing the most recent findings from developing and implementing new devices and technologies to improve the cancer results of genitourinary surgery. Therefore, this Special Issue aims to provide an open forum for those attempting to answer these questions, whether by reporting research or by providing comments for review articles. We look forward to receiving your submissions.

Dr. Lucio Dell'Atti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diagnostic tools
  • minimal invasive surgery
  • biomarkers
  • liquid biopsy
  • laparoscopic and robotic surgery
  • prostate cancer
  • kidney cancer
  • adrenal cancer
  • urinary tract cancer
  • bladder cancer
  • urethral cancer
  • testicular cancer
  • penis cancer

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Published Papers (1 paper)

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15 pages, 2215 KiB  
Case Report
Primary Prostatic Stromal Sarcoma: A Case Report and Review of the Literature
by Enes Erul, Ömer Gülpınar, Diğdem Kuru Öz, Havva Berber, Saba Kiremitci and Yüksel Ürün
Medicina 2024, 60(12), 1918; https://doi.org/10.3390/medicina60121918 - 22 Nov 2024
Viewed by 58
Abstract
Background and Objectives: Primary prostatic stromal sarcoma is an exceptionally rare urological malignancy, constituting less than 0.1% of all prostatic cancers. It poses a significant clinical challenge due to its aggressive behavior and poor prognosis. Materials and Methods: We report the [...] Read more.
Background and Objectives: Primary prostatic stromal sarcoma is an exceptionally rare urological malignancy, constituting less than 0.1% of all prostatic cancers. It poses a significant clinical challenge due to its aggressive behavior and poor prognosis. Materials and Methods: We report the case of a 34-year-old male who presented with nonspecific lower urinary tract symptoms, including dysuria and increased urinary frequency. The initial diagnostic workup, including digital rectal examination and Magnetic Resonance Imaging (MRI), revealed a lobulated lesion within the prostate. A transurethral resection (TUR) was performed for diagnostic purposes, and histopathological examination revealed a “malignant mesenchymal tumor”. The patient underwent a laparoscopic radical prostatectomy. The pathology report confirmed the diagnosis of prostatic stromal sarcoma. The postoperative follow-up, including systemic CT and MRI, showed no evidence of recurrence or metastasis thus far. Results: Multidisciplinary management is essential for optimizing treatment outcomes in all urologic malignancies; however, it becomes particularly challenging and crucial in rare cases such as primary prostatic stromal sarcoma. In our case, the patient benefited from a coordinated approach involving urology, pathology, and oncology, underscoring the importance of collaborative care for rare and aggressive tumors like this. This case highlights the importance of early detection, complete surgical excision, and consideration of adjuvant therapies, given the aggressive nature of the disease. The role of novel therapeutic strategies, including immunotherapy and targeted therapies, is also discussed in the context of metastatic sarcomas. Conclusions: This case underscores the critical need for a comprehensive, multidisciplinary approach to managing primary prostatic stromal sarcoma. Ongoing research on innovative therapies offers hope for improved outcomes in metastatic stages. Full article
(This article belongs to the Special Issue Current Developments in Diagnostic and Therapeutic Aspects of Genitourinary Tumors)
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