Cutaneous Complications of Targeted Cancer Therapy

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Dermatology".

Deadline for manuscript submissions: closed (15 July 2021) | Viewed by 3937

Special Issue Editor


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Guest Editor
Department of Dermatology, University of Padua, Padova, Italy
Interests: cutaneous oncology; immunodermatology
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Special Issue Information

Dear Colleagues,

Research in cancer development has led to the rapid emergence of numerous targeted anticancer therapies in the last decade. Targeted therapies, unlike standard chemotherapy agents that lead to systemic toxicities, are frequently associated with cutaneous adverse events, which may be responsible for dose reduction or therapy discontinuation. Given the rapid development of targeted anticancer treatments, dermatologists will be essential for the recognition of these cutaneous complications, particularly as the presence of dermatologic toxicities has been shown to have a positive correlation with response to therapy. Skin adverse events significantly influence the quality of life of patients under treatment with targeted drugs.

Authors are invited to submit research papers, reviews, clinical studies, and case reports concerning this issue.

Prof. Dr. Mauro Salvatore Alessandro Alaibac
Guest Editor

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Keywords

  • targeted therapies
  • immunotherapy
  • cutaneous toxicity
  • anti-cancer drugs
  • adverse drug reaction
  • skin rash

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Published Papers (1 paper)

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9 pages, 1292 KiB  
Case Report
Sarcoma as Second Cancer in a Childhood Cancer Survivor: Case Report, Large Population Analysis and Literature Review
by Thinh H. Nguyen, Monish Ram Makena, Siddhartha Yavvari, Maninder Kaur, Teresia Pham, Eduardo Urias, Narendra Panapitiya and Mohamad M. Al-Rahawan
Medicina 2020, 56(5), 224; https://doi.org/10.3390/medicina56050224 - 7 May 2020
Cited by 6 | Viewed by 2601
Abstract
The majority of pediatric patients are cured of their primary cancer with current advanced developments in pediatric cancer therapy. However, survivors often experience long-term complications from therapies for primary cancer. The delayed mortality rate has been decreasing with the effort to reduce the [...] Read more.
The majority of pediatric patients are cured of their primary cancer with current advanced developments in pediatric cancer therapy. However, survivors often experience long-term complications from therapies for primary cancer. The delayed mortality rate has been decreasing with the effort to reduce the therapeutic exposure of patients with pediatric cancers. Our study investigates the incidence of sarcoma as second cancer in pediatric cancer survivors. We present a 9-year-old male who survived embryonal hepatoblastoma diagnosed at 22 months of age. At 4.5 years of age, he presented with a non-metastatic primitive neuroectodermal tumor (PNET) of the left submandibular area. He has no evidence of recurrence of either cancer for 51 months after finishing all chemotherapy and radiotherapy. We used the Surveillance, Epidemiology, and End Results (SEER) database to identify the current rate of second sarcomas in pediatric cancer survivors. Our literature review and large population analysis emphasize the impact of sarcoma as a second malignancy and provide help to physicians caring for pediatric cancer survivors. Full article
(This article belongs to the Special Issue Cutaneous Complications of Targeted Cancer Therapy)
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