Lipidomics as a Diagnostic Tool: Lipid Metabolism and Its Related Human Diseases
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Lipid Metabolism".
Deadline for manuscript submissions: 29 November 2024 | Viewed by 3706
Special Issue Editors
Interests: lipidomics; metabolomics; PUFA; oxylipins; endocannabinoids; nutrition; metabolic disease
Special Issue Information
Dear Colleagues,
Lipid metabolism is involved in every facet of human physiology and the dysregulation of these processes is implicated in the onset and/or progression of various diseases. In recent years, we have seen lipidomics used as a powerful tool to identify potential lipid biomarkers. However, we are only at the tip of the proverbial iceberg. There are an estimated 60,000 lipid species, though only several thousand of these have been identified with high confidence. Despite this gap, those identified lipid species are shown to be integral to human physiology and pathology, leaving a breadth of information yet to be discovered. With advances in instrumentation and computational methods, we are learning more about the function of distinct lipids in the human lipidome as well as the delicate cross-talk between lipids and protein cofactors.
In this Special Issue, we seek to explore the use of lipidomics to better understand lipid metabolism. We aim to provide a more in-depth look into the human lipidome to potentially discover novel lipids, lipid mediators, or co-factors that are linked to human disease.
Dr. Kristal M. Maner-Smith
Dr. Arion J. Kennedy
Guest Editors
Manuscript Submission Information
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Keywords
- lipidomics
- metabolomics
- nutrition
- bioactive lipids
- signaling lipids
- polyunsaturated fatty acids
- oxylipins
- endocannabinoids
- sphingolipids
- ceramides
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