Mass Spectrometry-Based Metabolomics in Health and Disease: Targeted Analysis
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Advances in Metabolomics".
Deadline for manuscript submissions: closed (25 October 2024) | Viewed by 1158
Special Issue Editor
Special Issue Information
Dear Colleagues,
Metabolomics is a fascinating and growing field that aims to identify and quantify small molecules derived from cell and body metabolism. Biomarker discovery, drug discovery, toxicological testing, and clinical and preclinical studies are areas in which metabolomics plays a key role.
The nature of the metabolites, particularly their complexity and heterogeneity, the dynamic range of the measurement technique, the extraction protocols, and the myriad of variables related to the variation in these metabolites, remains as the main challenge. However, metabolomics is a very powerful approach for the characterisation of metabolites and metabolic pathways in health and disease, reflecting the results of the complex network of biochemical reactions that occur in living systems. Here, chromatography coupled with mass spectrometry (MS)-based metabolomics is the gold standard due to its beneficial bioanalytic performance characteristics such as high selectivity and high sensitivity, providing innovative tools for novel diagnostic and prognostic approaches. In this context, targeted analysis is key to analyse measurable metabolites in biological samples or a set of preselected metabolites. However, many challenges need to be overcome, including the proper validation of methods, sample selection and quality control, and complex statistical data analysis. Therefore, new mass spectrometry-based metabolomics methods and the discovery of interesting biomarkers are the main targets of this Special Issue.
Dr. Emanuele Porru
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- mass spectrometry
- metabolomics
- metabolic diseases
- chromatography
- biomarkers
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
