Cardiometabolic Effect of the Mediterranean Diet

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: closed (15 July 2022) | Viewed by 5453

Special Issue Editors


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Guest Editor
Clinical and Health Sciences & Alliance for Research in Exercise, Nutrition and Activity (ARENA) University of South Australia, Adelaide, SA 5001, Australia
Interests: Mediterranean diets; fatty acids; n-3 fatty acids; sports nutrition; inflammation; inflammatory-based diseases

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Guest Editor
School of Health and Behavioural Sciences, University of the Sunshine Coast, Sippy Downs, QLD 4556, Australia
Interests: mediterranean diet to support healthy ageing; sarcopenia; frailty; physical function; nutrition and type 2 diabetes
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Special Issue Information

Dear Colleagues,

The Mediterranean diet (MedDiet) is commonly recognized as a health-promoting dietary pattern due to its familiar characteristics, including the regular consumption of vegetables, fruits, nuts, legumes, unprocessed cereals, and extra-virgin olive oil.

Adherence to a MedDiet affords protection from insulin resistance-related cardiometabolic conditions, including type 2 diabetes (T2DM) and cardiovascular disease, and is inversely associated with central obesity in both epidemiological studies and dietary intervention studies. These benefits are also independent of caloric restriction and weight loss due to the large number of functional foods and nutraceuticals present within the dietary pattern. Being predominately plant-based, the MedDiet is naturally low in saturated fat and rich in several functional components, including vitamins and minerals, carotenoids, unsaturated fatty acids, and phenolic compounds. These components of the MedDiet have antioxidant and anti-inflammatory properties which are involved in preventing and ameliorating the pathophysiology involved in numerous cardiometabolic disorders.

We therefore invite manuscripts for this Special Issue describing epidemiological, interventional and implementation studies which explore the potential efficacy of MedDiet adherence on cardiometabolic health in all populations of health and disease.

Dr. Evangeline Mantzioris
Dr. Anthony Villani
Guest Editors

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Keywords

  • Mediterranean diet
  • human metabolism
  • cardiovascular health
  • metabolic health
  • obesity
  • weight loss
  • biomarkers
  • experimental studies
  • epidemiological studies

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Published Papers (1 paper)

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18 pages, 1076 KiB  
Protocol
Efficacy, Feasibility and Acceptability of a Mediterranean Diet Intervention on Hormonal, Metabolic and Anthropometric Measures in Overweight and Obese Women with Polycystic Ovary Syndrome: Study Protocol
by Nicole Scannell, Lisa Moran, Evangeline Mantzioris, Stephanie Cowan and Anthony Villani
Metabolites 2022, 12(4), 311; https://doi.org/10.3390/metabo12040311 - 31 Mar 2022
Cited by 4 | Viewed by 4936
Abstract
Polycystic ovary syndrome (PCOS) is a common endocrine condition in reproductive-aged women associated with metabolic, reproductive and psychological features. Lifestyle modification (diet/physical activity) is considered first-line treatment for PCOS. However, there is limited high-quality evidence to support therapeutic dietary interventions for PCOS beyond [...] Read more.
Polycystic ovary syndrome (PCOS) is a common endocrine condition in reproductive-aged women associated with metabolic, reproductive and psychological features. Lifestyle modification (diet/physical activity) is considered first-line treatment for PCOS. However, there is limited high-quality evidence to support therapeutic dietary interventions for PCOS beyond general population-based healthy eating guidelines. Adherence to a Mediterranean diet (MedDiet), with or without energy restriction, improves cardiometabolic health in populations including persons with or at high risk of cardiovascular disease and type 2 diabetes. However, there is limited research examining the MedDiet in PCOS. Therefore, this 12 week randomized controlled trial will investigate the efficacy of a MedDiet on cardiometabolic and hormonal parameters and explore its acceptability and feasibility in PCOS. Forty-two overweight and obese women with PCOS (aged 18–45 years) will be randomized to receive dietary advice consistent with Australian Dietary Guidelines or an ad libitum MedDiet intervention. All participants will receive fortnightly counselling to facilitate behaviour change. The primary outcomes will be changes in insulin resistance, glucose, total testosterone and sex hormone-binding globulin. Secondary outcomes include changes in body weight and feasibility and acceptability of the MedDiet intervention. The results of this study will provide further evidence on specific dietary approaches for management of PCOS. Full article
(This article belongs to the Special Issue Cardiometabolic Effect of the Mediterranean Diet)
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