Energy Metabolism in Neurodegenerative Diseases
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 2198
Special Issue Editors
Interests: energy metabolism; animal models; huntington’s disease; neurodegener-ative diseases; heart; skeletal muscle
Special Issues, Collections and Topics in MDPI journals
Interests: pathophysiology of neurodegenerative diseases; neuroinflammatory pathways; animal behavior; genetic disorders; molecular mechanisms
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The incidence of age-related disorders, specifically neurodegenerative diseases, has been on the rise in correlation with the increase in life expectancy observed over the past century. Diseases such as Alzheimer's, Parkinson's, Huntington's, and multiple sclerosis are chronic conditions characterized by the progressive loss of neurons in various motor, sensory, or cognitive systems. A growing body of evidence suggests a strong link between metabolic dysregulation and the pathogenesis of neurodegeneration. Metabolic changes, such as alterations in energy metabolism, oxidative stress, and mitochondrial dysfunction, have emerged as key contributors to the neurodegenerative process. These metabolic disturbances can disrupt cellular homeostasis, impair neuronal function, and ultimately lead to neuronal death. Understanding the intricate interplay between metabolic alterations and neurodegeneration is of the utmost importance in unraveling the underlying mechanisms of these age-related disorders and identifying potential therapeutic targets.
This Special Issue will highlight new insights into energy metabolism in neurodegenerative diseases. Moreover, studies that focus on the identification of biomarkers, therapeutic targets, and future treatments related to metabolic pathways are also welcome.
Dr. Marta Tomczyk
Dr. Magdalena Podlacha
Guest Editors
Manuscript Submission Information
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Keywords
- energy metabolism
- neurodegeneration
- neurodegenerative disease
- Alzheimer’s disease
- Parkinson’s disease
- Huntington’s disease
- amyotrophic lateral sclerosis
- spinal muscular atrophy
- Lewy body disease
- multiple sclerosis
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