Zebrafish: A Model for the Study of Human Metabolism Diseases
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".
Deadline for manuscript submissions: closed (31 August 2021) | Viewed by 5853
Special Issue Editor
Special Issue Information
Dear Colleagues,
Zebrafish are a powerful tool to study a wide variety of human diseases, from developmental abnormalities to cancer. They have recently emerged as an important model system in research on metabolic function and metabolic disease. The metabolism involves a complex interplay between multiple organ systems and endocrine signalling. This level of complexity cannot be recreated in in vitro systems. Zebrafish possess all of the key organs needed for metabolic function in humans, and many of the proteins and pathways involved in the metabolism are highly conserved between zebrafish and mammals. Additionally, zebrafish are a low-cost model system for use in large-scale assays, are relatively easy to genetically manipulate, and are excellent for live animal imaging. This Special Issue will highlight the use of zebrafish in research related to human metabolism and metabolic disorders, either at the whole-organism level or in a single cell. Topics can include, but are not limited to, zebrafish models of metabolic disease, new technological applications, genomic approaches, high-throughput chemical screening, cross-species data comparisons, and biomarkers.
Dr. Jessica Blackburn
Guest Editor
Manuscript Submission Information
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Keywords
- Zebrafish
- Metabolomics
- Transgenic
- Imaging
- Mass Spectrometry
- Metabolic Regulation
- Obesity
- Diabetes
- Cancer
- Drug Discovery
- Regeneration
- Toxicology
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